In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice. (Q40803071)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11376562%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

In vivo effects of a histone deacetylase inhibitor, FK228, on human acute promyelocytic leukemia in NOD / Shi-scid/scid mice (English)

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7 November 2019

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acute promyelocytic leukemia

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3

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7 November 2019

author name string

H Kosugi

1

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7 November 2019

M Ito

2

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7 November 2019

M Towatari

4

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7 November 2019

M Ito

5

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7 November 2019

R Ueda

6

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7 November 2019

H Saito

7

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7 November 2019

T Naoe

8

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7 November 2019

publication date

1 May 2001

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7 November 2019

number of pages

8

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Japanese Journal of Cancer Research

inferred from page(s)

published in

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7 November 2019

volume

92

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7 November 2019

page(s)

529-536

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7 November 2019

issue

5

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Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

7 November 2019

cites work

1 reference

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Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all-trans retinoic acid

17 June 2018

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The language of covalent histone modifications

17 June 2018

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

17 June 2018

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Histone deacetylase inhibitors are the potent inducer/enhancer of differentiation in acute myeloid leukemia: a new approach to anti-leukemia therapy

17 June 2018

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Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia

17 June 2018

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Three proteins define a class of human histone deacetylases related to yeast Hda1p

17 June 2018

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A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

17 June 2018

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Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

17 June 2018

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FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

17 June 2018

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Acute promyelocytic leukemia: relieving repression induces remission.

17 June 2018

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Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase

17 June 2018

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Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

17 June 2018

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Role of the histone deacetylase complex in acute promyelocytic leukaemia

17 June 2018

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

17 June 2018

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A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RAR alpha mutation

17 June 2018

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Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

17 June 2018

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Role of CBP/P300 in nuclear receptor signalling

17 June 2018

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Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway

17 June 2018

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Establishment of a human acute promyelocytic leukemia-ascites model in SCID mice.

17 June 2018

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Histone deacetylase: a regulator of transcription

17 June 2018

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The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

17 June 2018

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Acute promyelocytic leukemia: from genetics to treatment

17 June 2018

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Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase

17 June 2018

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FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice

17 June 2018

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Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17).

17 June 2018

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All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia.

17 June 2018

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Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

17 June 2018

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Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

17 June 2018

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

17 June 2018

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

17 June 2018

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Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.

17 June 2018

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Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase

21 January 2018

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Acute promyelocytic leukemia

21 January 2018

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12 December 2020

Mutant AF-2 domain of PML-RARalpha in retinoic acid-resistant NB4 cells: differentiation induced by RA is triggered directly through PML-RARalpha and its down-regulation in acute promyelocytic leukemia

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12 December 2020

Determination of the antitumor agent depsipeptide in plasma by liquid chromatography on serial octadecyl stationary phases

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12 December 2020

Depsipeptide (FR901228, NSC-630176) pharmacokinetics in the rat by LC/MS/MS

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12 December 2020

Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway

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12 December 2020

Effects of trichostatins on differentiation of murine erythroleukemia cells

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12 December 2020

10.1111/J.1349-7006.2001.TB01126.X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11376562%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11376562%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11376562%20AND%20SRC:MED&resulttype=core&format=json