The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells (Q40806094)

23 September 2017

The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells (English)

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23 September 2017

I A Mayer

1

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23 September 2017

A Verma

2

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23 September 2017

I M Grumbach

3

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23 September 2017

S Uddin

4

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23 September 2017

F Lekmine

5

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23 September 2017

F Ravandi

6

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23 September 2017

B Majchrzak

7

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23 September 2017

S Fujita

8

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23 September 2017

E N Fish

9

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23 September 2017

L C Platanias

10

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23 September 2017

language of work or name

English

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publication date

15 May 2001

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

276

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23 September 2017

30

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23 September 2017

28570-28577

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Interferons and their actions

23 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M011685200

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

STATs and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

How cells respond to interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Signaling pathways activated by interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Cytokine therapeutics: lessons from interferon alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Interferon-alpha therapy for chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Structural organization of the bcr gene and its role in the Ph' translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Role of the adapter protein CRKL in signal transduction of normal hematopoietic and BCR/ABL-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Activation of a CrkL-stat5 signaling complex by type I interferons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Activation of the p38 mitogen-activated protein kinase by type I interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Interferon-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

The type I interferon receptor mediates tyrosine phosphorylation of the CrkL adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Definition of receptor binding domains in interferon-alpha

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M011685200

CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Structural basis of inhibitor selectivity in MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M011685200

21 January 2018

Identifiers

DOI

10.1074/JBC.M011685200

1 reference

23 September 2017

1 reference