SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma (Q40807388)

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scientific article published on 7 May 2001

Language	Label	Description	Also known as
English	SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma	scientific article published on 7 May 2001

Statements

scholarly article

1 reference

Europe PubMed Central

23 September 2017

SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma (English)

1 reference

Europe PubMed Central

23 September 2017

author name string

S Cottet

1

1 reference

Europe PubMed Central

23 September 2017

P Dupraz

2

1 reference

Europe PubMed Central

23 September 2017

F Hamburger

3

1 reference

Europe PubMed Central

23 September 2017

W Dolci

4

1 reference

Europe PubMed Central

23 September 2017

M Jaquet

5

1 reference

Europe PubMed Central

23 September 2017

B Thorens

6

1 reference

Europe PubMed Central

23 September 2017

language of work or name

0 references

publication date

7 May 2001

1 reference

Europe PubMed Central

23 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

23 September 2017

276

1 reference

Europe PubMed Central

23 September 2017

25862-25870

1 reference

Europe PubMed Central

23 September 2017

28

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Europe PubMed Central

23 September 2017

Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma -mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

The beta cell in autoimmune diabetes: many mechanisms and pathways of loss

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Systemic bias of cytokine production toward cell-mediated immune regulation in IDDM and toward humoral immunity in Graves' disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

IFN-gamma action on pancreatic beta cells causes class I MHC upregulation but not diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

STATs and gene regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Negative regulation of cytokine signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

A new protein containing an SH2 domain that inhibits JAK kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Structure and function of a new STAT-induced STAT inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

A family of cytokine-inducible inhibitors of signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Effects of prolonged exposure in vitro to interferon-gamma and tumour necrosis factor-alpha on nitric oxide and insulin production of rat pancreatic islets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

T helper cell subsets in insulin-dependent diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Interferon-gamma independently activates the MHC class I antigen processing pathway and diminishes glucose responsiveness in pancreatic beta-cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Expression of intercellular adhesion molecule 1 on pancreatic beta-cells accelerates beta-cell destruction by cytotoxic T-cells in murine autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Human pancreatic islet beta-cell destruction by cytokines is independent of nitric oxide production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Mechanisms of cytokine-induced destruction of rat insulinoma cells: the role of nitric oxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

Nitric oxide production and Fas surface expression mediate two independent pathways of cytokine-induced murine beta-cell damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

DNA fragmentation is an early event in cytokine-induced islet beta-cell destruction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103235200

21 January 2018

CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells

1 reference

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21 January 2018

Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels

1 reference

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21 January 2018

Tumor necrosis factor-alpha and interferon-gamma inhibit insulin secretion and cause DNA damage in unweaned-rat islets. Extent of nitric oxide involvement

1 reference

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21 January 2018

Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M103235200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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