The p53 tumor suppressor gene frequently is altered in gynecologic cancers (Q40808817)

23 September 2017

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title

The p53 tumor suppressor gene frequently is altered in gynecologic cancers (English)

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23 September 2017

6

Bast RC Jr

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ORCID Public Data File 2021

23 September 2017

1

Berchuck A

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23 September 2017

Kohler MF

2

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23 September 2017

Marks JR

series ordinal

3

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23 September 2017

Wiseman R

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4

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23 September 2017

Boyd J

series ordinal

5

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23 September 2017

language of work or name

English

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publication date

1 January 1994

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American Journal of Obstetrics and Gynecology

23 September 2017

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23 September 2017

170

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23 September 2017

246-252

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23 September 2017

1 Pt 1

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Human p53 gene localized to short arm of chromosome 17

23 September 2017

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

The p53 tumour suppressor gene

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

The p53 proto-oncogene can act as a suppressor of transformation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

p53 overexpression in formalin-fixed, paraffin-embedded tissue detected by immunohistochemistry

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Mutations in the p53 gene occur in diverse human tumour types

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

p53 mutations in human cancers

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

TP53 tumor suppressor gene: a model for investigating human mutagenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

High incidence of p53 gene mutation in human ovarian cancer and its association with nuclear accumulation of p53 protein and tumor DNA aneuploidy

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

p53 gene mutations and protein accumulation in human ovarian cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Expression of p53 protein in colorectal cancer and its relationship to short-term prognosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Spectrum of mutation and frequency of allelic deletion of the p53 gene in ovarian cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Genetic alterations during colorectal-tumor development

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Clonal origin of epithelial ovarian carcinoma: analysis by loss of heterozygosity, p53 mutation, and X-chromosome inactivation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Too many rodent carcinogens: mitogenesis increases mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies. II. Invasive epithelial ovarian cancers in white women. Collaborative Ovarian Cancer Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Overexpression of HER-2/neu in endometrial cancer is associated with advanced stage disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

High level expression of fms proto-oncogene mRNA is observed in clinically aggressive human endometrial adenocarcinomas.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

p53 gene mutations in human endometrial carcinoma

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Mutation of the p53 tumor-suppressor gene is not a feature of endometrial hyperplasias.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Association between poor prognosis in early-stage invasive cervical carcinomas and non-detection of HPV DNA

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Clonal p53 mutation in primary cervical cancer: association with human-papillomavirus-negative tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

Increased expression of mutant forms of p53 oncogene in primary lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9378%2894%2970414-7

10.1016/S0002-9378(94)70414-7

7 January 2021

Identifiers

DOI

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23 September 2017

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