Activation of c-Abl kinase activity and transformation by a chemical inducer of dimerization (Q40810145)

23 September 2017

Activation of c-Abl kinase activity and transformation by a chemical inducer of dimerization (English)

1 reference

23 September 2017

Smith KM

1

1 reference

PubMed ID

11320088

23 September 2017

Van Etten RA

series ordinal

2

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PubMed ID

11320088

23 September 2017

language of work or name

English

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publication date

24 April 2001

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

276

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23 September 2017

26

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23 September 2017

24372-24379

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The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

The nuclear tyrosine kinase c-Abl negatively regulates cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Cycling, stressed-out and nervous: cellular functions of c-Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Crystal structure of the Src family tyrosine kinase Hck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

An intramolecular SH3-domain interaction regulates c-Abl activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Bcr encodes a GTPase-activating protein for p21rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Controlling signal transduction with synthetic ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

A chimeric receptor/oncogene that can be regulated by a ligand in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

A general strategy for producing conditional alleles of Src-like tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Oligomeric structure of the human EphB2 receptor SAM domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Signal transduction by receptors with tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Hormonal regulation of the Rous sarcoma virus src gene via a heterologous promoter defines a threshold dose for cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Cells arrested in G1 by the v-Abl tyrosine kinase do not express cyclin A despite the hyperphosphorylation of RB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Nuclear localization of v-Abl leads to complex formation with cyclic AMP response element (CRE)-binding protein and transactivation through CRE motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

Retroviral vectors for production of interleukin-12 in the bone marrow to induce a graft-versus-leukemia effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M100786200

21 January 2018

Identifiers

DOI

10.1074/JBC.M100786200

1 reference

23 September 2017

1 reference

PubMed ID

11320088