The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state. (Q40812232)

PubMed publication ID

11306612

23 September 2017

title

The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762528&resulttype=core&format=json

12 May 2020

author name string

J W Lynch

1

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12 May 2020

N L Han

2

1 reference

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12 May 2020

J Haddrill

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762528&resulttype=core&format=json

12 May 2020

K D Pierce

4

1 reference

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12 May 2020

P R Schofield

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762528&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 April 2001

1 reference

PubMed publication ID

11306612

23 September 2017

published in

Journal of Neuroscience

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12 May 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762528&resulttype=core&format=json

12 May 2020

issue

8

1 reference

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12 May 2020

page(s)

2589-2599

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762528&resulttype=core&format=json

12 May 2020

1 reference

12 December 2020

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

1 reference

12 December 2020

Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.

1 reference

12 December 2020

Mapping the conformational wave of acetylcholine receptor channel gating

1 reference

12 December 2020

Gating of alpha3beta4 neuronal nicotinic receptor can be controlled by the loop M2-M3 of both alpha3 and beta4 subunits

1 reference

12 December 2020

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

1 reference

12 December 2020

Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates

1 reference

12 December 2020

Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate

1 reference

12 December 2020

Novel GLRA1 missense mutation (P250T) in dominant hyperekplexia defines an intracellular determinant of glycine receptor channel gating

1 reference

12 December 2020

Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes

1 reference

12 December 2020

Benzodiazepines induce a conformational change in the region of the gamma-aminobutyric acid type A receptor alpha(1)-subunit M3 membrane-spanning segment

1 reference

12 December 2020

Contribution of the beta subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor

1 reference

12 December 2020

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

12 December 2020

A single residue in the M2-M3 loop is a major determinant of coupling between binding and gating in neuronal nicotinic receptors.

1 reference

12 December 2020

State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor. Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit

1 reference

12 December 2020

Neuronal nicotinic receptors: molecular organization and regulations

1 reference

12 December 2020

The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element

1 reference

12 December 2020

A residue in the middle of the M2-M3 loop of the beta4 subunit specifically affects gating of neuronal nicotinic receptors.

1 reference

12 December 2020

Mutations in the alpha 1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia

1 reference

12 December 2020

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.

1 reference

12 December 2020

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit

1 reference

12 December 2020

Mutational analysis of familial and sporadic hyperekplexia

1 reference

12 December 2020

The role of an alpha subtype M2-M3 His in regulating inhibition of GABAA receptor current by zinc and other divalent cations

1 reference

12 December 2020

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

1 reference

12 December 2020

Substituted-cysteine accessibility method

1 reference

12 December 2020

Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists

1 reference

12 December 2020

Analysis of GLRA1 in hereditary and sporadic hyperekplexia: a novel mutation in a family cosegregating for hyperekplexia and spastic paraparesis

1 reference

12 December 2020

Identification of transduction elements for benzodiazepine modulation of the GABA(A) receptor: three residues are required for allosteric coupling

1 reference

12 December 2020

Gamma-aminobutyric acid increases the water accessibility of M3 membrane-spanning segment residues in gamma-aminobutyric acid type A receptors

1 reference

12 December 2020

Evidence for recessive as well as dominant forms of startle disease (hyperekplexia) caused by mutations in the alpha 1 subunit of the inhibitory glycine receptor

1 reference

12 December 2020

Mutagenesis of the GABA rho 1 receptor alters agonist affinity and channel gating

1 reference

12 December 2020

Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.

1 reference

12 December 2020

The extracellular linker of muscle acetylcholine receptor channels is a gating control element

1 reference

12 December 2020

Specific binding sites for alcohols and anesthetics on ligand-gated ion channels

1 reference

12 December 2020

10.1523/JNEUROSCI.21-08-02589.2001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762528&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6762528&resulttype=core&format=json

12 May 2020

PubMed publication ID

11306612

1 reference