When drug inactivation renders the target irrelevant to antibiotic resistance: a case story with beta-lactams (Q40824709)

24 September 2017

When drug inactivation renders the target irrelevant to antibiotic resistance: a case story with beta-lactams (English)

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24 September 2017

antibiotic resistance

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Lakaye B

1

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24 September 2017

Dubus A

2

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24 September 2017

Lepage S

3

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24 September 2017

Groslambert S

4

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24 September 2017

Frère JM

5

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24 September 2017

language of work or name

English

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publication date

1 January 1999

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24 September 2017

Molecular Microbiology

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24 September 2017

31

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24 September 2017

1

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24 September 2017

89-101

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Nucleotide sequences of the genes coding for the TEM-like beta-lactamases IRT-1 and IRT-2 (formerly called TRI-1 and TRI-2).

24 September 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Improved sensitivity in assays for binding of novel beta-lactam antibiotics to penicillin-binding proteins of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Can penicillins and other beta-lactam antibiotics be used to treat tuberculosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Affinities of penicillins and cephalosporins for the penicillin-binding proteins of Escherichia coli K-12 and their antibacterial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

A dramatic change in the rate-limiting step of beta-lactam hydrolysis results from the substitution of the active-site serine residue by a cysteine in the class-C beta-lactamase of Enterobacter cloacae 908R

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Quantitative relationship between sensitivity to beta-lactam antibiotics and beta-lactamase production in gram-negative bacteria--II. Non-steady-state treatment and progress curves

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

A survey of the kinetic parameters of class C beta-lactamases. Penicillins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

A survey of the kinetic parameters of class C beta-lactamases. Cephalosporins and other beta-lactam compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

A new, highly sensitive method for the detection and quantification of penicillin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Cytosolic intermediates for cell wall biosynthesis and degradation control inducible beta-lactam resistance in gram-negative bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Synthesis, purification and kinetic properties of fluorescein-labelled penicillins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Kinetic properties of the Bacillus licheniformis penicillin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Outer membrane permeability and beta-lactamase stability of dipolar ionic cephalosporins containing methoxyimino substituents

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Immunological detection of penicillin-binding protein 2' in clinical isolates of methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Presence of an additional penicillin-binding protein in methicillin-resistant Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, and Staphylococcus simulans with a low affinity for methicillin, cephalothin, and cefamand

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Imipenem- and meropenem-resistant mutants of Enterobacter cloacae and Proteus rettgeri lack porins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Evolution of an inducible penicillin-target protein in methicillin-resistant Staphylococcus aureus by gene fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Trapping of nonhydrolyzable cephalosporins by cephalosporinases in Enterobacter cloacae and Pseudomonas aeruginosa as a possible resistance mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Role of beta-lactam hydrolysis in the mechanism of resistance of a beta-lactamase-constitutive Enterobacter cloacae strain to expanded-spectrum beta-lactams

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Mechanism of action of DD-peptidases: role of asparagine-161 in the Streptomyces R61 DD-peptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Function of the Outer Membrane of Escherichia coli as a Permeability Barrier to Beta-Lactam Antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

The Role of Penicillin-Binding Proteins for β-Lactam Resistance in a β-Lactamase ProducingBacteroides uniformisStrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Quantitative relationship between sensitivity to beta-lactam antibiotics and beta-lactamase production in gram-negative bacteria--I. Steady-state treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Genetic control of beta-lactamase production in Enterobacter cloacae

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Interaction of clavulanate with class C beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Molecular evolution of a class C beta-lactamase extending its substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

Contribution of β-lactamase production to the resistance of mycobacteria to β-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2958.1999.01150.X

10.1046/J.1365-2958.1999.01150.X

21 January 2018

Identifiers

DOI

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24 September 2017

1 reference