Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells. (Q40831704)

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English	Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells.	scientific article

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5 November 2019

Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells (English)

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5 November 2019

Christopher G. Proud

4

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5 November 2019

Terence P. Herbert

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5 November 2019

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G R Kilhams

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5 November 2019

I H Batty

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5 November 2019

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1 April 2000

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5 November 2019

Journal of Biological Chemistry

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5 November 2019

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5 November 2019

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5 November 2019

11249-11256

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5 November 2019

Molecular mechanisms for the control of translation by insulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Stimulation of translation in 3T3-L1 cells in response to insulin and phorbol ester is directly correlated with increased phosphate labelling of initiation factor (eIF-) 4F and ribosomal protein S6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Insulin and phorbol ester stimulate initiation factor eIF-4E phosphorylation by distinct pathways in Chinese hamster ovary cells overexpressing the insulin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Regulation of translation initiation factors by signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Polypyrimidine tracts and their binding proteins: regulatory sites for posttranscriptional modulation of gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Regulation of eIF-4E BP1 phosphorylation by mTOR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Mechanism of activation and function of protein kinase B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Insulin activates a 70-kDa S6 kinase through serine/threonine-specific phosphorylation of the enzyme polypeptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Insulin activates a PD 098059-sensitive kinase that is involved in the regulation of p70S6K and PHAS-I.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Phorbol esters stimulate phosphatidylinositol 3,4,5-trisphosphate production in 3T3-L1 adipocytes: implications for stimulation of glucose transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Potentiation of insulin-induced phosphatidylinositol-3 kinase activity by phorbol ester is mediated by protein kinase C epsilon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.11249

21 January 2018

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10.1074/JBC.275.15.11249

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5 November 2019

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