Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells (Q40839150)

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English	Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells	scientific article

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scholarly article

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Europe PubMed Central

24 September 2017

Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells (English)

1 reference

Europe PubMed Central

24 September 2017

author name string

K T Nguyen

1

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Europe PubMed Central

24 September 2017

W J Wang

2

1 reference

Europe PubMed Central

24 September 2017

J L Chan

3

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Europe PubMed Central

24 September 2017

L H Wang

4

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Europe PubMed Central

24 September 2017

language of work or name

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publication date

1 November 2000

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Europe PubMed Central

24 September 2017

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Europe PubMed Central

24 September 2017

19

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Europe PubMed Central

24 September 2017

47

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Europe PubMed Central

24 September 2017

5385-5397

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Europe PubMed Central

24 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203911

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Ras-independent transformation by v-Src

1 reference

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21 January 2018

Akt activation by growth factors is a multiple-step process: the role of the PH domain

1 reference

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21 January 2018

Stat3 activation is required for cellular transformation by v-src

1 reference

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Effect of dimerization on signal transduction and biological function of oncogenic Ros, insulin, and insulin-like growth factor I receptors.

1 reference

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Stat5 is a physiological substrate of the insulin receptor

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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

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Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

1 reference

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Mechanisms and consequences of activation of protein kinase B/Akt

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Functional insulin receptors are overexpressed in thyroid tumors: is this an early event in thyroid tumorigenesis?

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Effect of tyrosine mutations on the kinase activity and transforming potential of an oncogenic human insulin-like growth factor I receptor.

1 reference

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

1 reference

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Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development.

1 reference

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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

1 reference

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Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.

1 reference

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21 January 2018

Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

1 reference

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21 January 2018

Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src.

1 reference

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Molecular basis of the activation of the tumorigenic potential of Gag-insulin receptor chimeras

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The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor

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Mitogen-activated protein kinases: specific messages from ubiquitous messengers

1 reference

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Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

1 reference

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Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

1 reference

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21 January 2018

Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

1 reference

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21 January 2018

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

1 reference

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Receptor protein-tyrosine kinases and their signal transduction pathways

1 reference

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Activation of transforming potential of the human insulin receptor gene

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Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product

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Functional properties of two naturally occurring isoforms of the human insulin receptor in Chinese hamster ovary cells

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Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

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Identification of insulin and insulin-like growth factor I (IGF I) receptors in ovarian cancer tissue

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c-Src, receptor tyrosine kinases, and human cancer

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Regulation, substrates and functions of src

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Differentially expressed gene products in glioblastoma cells suppressed for tumorigenicity.

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IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase

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Characterization of insulin-like growth factor I receptors and growth effects in human lung cancer cell lines

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Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism

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Human cellular src gene product: identification of the myristoylated pp60c-src and blockage of its myristoyl acylation with N-fatty acyl compounds resulted in the suppression of colony formation

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The role of the insulin-like growth factor system in human cancer

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Expression of insulin-like growth factor receptors in primary human thyroid neoplasms

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Identifiers

10.1038/SJ.ONC.1203911

1 reference

Europe PubMed Central

24 September 2017

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1 reference

Europe PubMed Central

24 September 2017

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