Evolving concepts about the role of acidosis in ischemic neuropathology (Q40840232)

24 September 2017

1 reference

title

Evolving concepts about the role of acidosis in ischemic neuropathology (English)

1 reference

24 September 2017

Tombaugh GC

1

1 reference

PubMed ID

8360684

24 September 2017

Sapolsky RM

series ordinal

2

1 reference

PubMed ID

8360684

24 September 2017

language of work or name

English

0 references

publication date

1 September 1993

1 reference

Journal of Neurochemistry

24 September 2017

1 reference

24 September 2017

61

1 reference

24 September 2017

793-803

1 reference

24 September 2017

3

1 reference

Selective modulation of NMDA responses by reduction and oxidation

24 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-D-aspartate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Biological differences between ischemia, hypoglycemia, and epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Chlorpromazine protects brain tissue in hypoxia by delaying spreading depression-mediated calcium influx.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Concentration of carbon dioxide, interstitial pH and synaptic transmission in hippocampal formation of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

The regulation and modulation of pH in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

The Role Of Glutamate Neurotoxicity In Hypoxic-Ischemic Neuronal Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Electrophysiological properties of rat CA1 pyramidal neurones in vitro modified by changes in extracellular bicarbonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Hippocampal cell death following ischemia: Effects of brain temperature and anesthesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Relations between postmortem alterations and glycolytic metabolism in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Selective vulnerability of cultured cortical glia to injury by extracellular acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Roles of calcium and pH in activation of eggs of the medaka fish, Oryzias latipes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

MK-801 is neuroprotective in gerbils when administered during the post-ischaemic period

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Excitotoxic index — a biochemical marker of selective vulnerability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Concurrent measurement of (Na+,K+)-ATPase activity and lipid peroxides in rat brain following reversible global ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

The effects of extracellular acidosis on neurons and glia in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Distribution of intracellular pH in the rat brain cortex after global ischemia as measured by color film histophotometry of neutral red.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Influence of preischemic hyperglycemia on osmolality and early postischemic edema in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Carbon dioxide uncouples dye-coupled neuronal aggregates in neocortical slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Progressive derangement of periinfarct viable tissue in ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Features of astrocytic function apparently involved in the response of central nervous tissue to ischemia-hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Lactic acidosis and recovery of mitochondrial function following forebrain ischemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Reversibility of ischemic brain damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Quantitative analysis of glucose after transient ischemia in the gerbil hippocampus by light and electron microscope radioautography

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Neurons sensitive to pH in slices of the rat ventral medulla oblongata

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Animal models of stroke: are they relevant to human disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Extracellular pH in the brain during ischemia: relationship to the severity of lactic acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

NMDA application potentiates synaptic transmission in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

The CSF HCO3− increase in hypercapnia relationship to HCO3−, glutamate, glutamine and NH3 in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Cation transport and membrane potential properties of primary astroglial cultures from neonatal rat brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Analysis of vasoactivity of local pH, PCO2 and bicarbonate on pial vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Astrocytic acidosis in hyperglycemic and complete ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Hydrogen ions kill brain at concentrations reached in ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Relation of hyperglycemia early in ischemic brain infarction to cerebral anatomy, metabolism, and clinical outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

The luxury-perfusion syndrome and its possible relation to acute metabolic acidosis localised within the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Redox modulation of NMDA receptor-mediated toxicity in mammalian central neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Influence of tissue acidosis upon restitution of brain energy metabolism following total ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Critical levels of extracellular glutamate mediating gerbil hippocampal delayed neuronal death during hypothermia: Brain microdialysis study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Nervous system effects of cardiac arrest in monkeys. Preservation of vision

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Brain tissue pH after global brain ischemia and barbiturate loading in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Effects of phenobarbital in cerebral ischemia. Part I: cerebral energy metabolism during pronounced incomplete ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Brain tissue concentrations of ATP, phosphocreatine, lactate, and tissue pH in relation to reduced cerebral blood flow following experimental acute middle cerebral artery occlusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Classification of ischemic-induced damage to Na+, K+-ATPase in gerbil forebrain. Modification by therapeutic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Relationship between putrescine content and density of ischemic cell damage in the brain of mongolian gerbils: effect of nimodipine and barbiturate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Regional cerebral blood flow in apoplexy due to occlusion of the middle cerebral artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Effects of insulin-induced hypoglycemia on intracellular pH and impedance in the cerebral cortex of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

What causes infarction in ischemic brain?: The Robert Wartenberg Lecture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Moderate hyperglycemia augments ischemic brain damage: a neuropathologic study in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Temporal profile of neuronal damage in a model of transient forebrain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Brain Lactic Acidosis and Ischemic Cell Damage: 1. Biochemistry and Neurophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Selective vulnerability of the hippocampus in brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

The mechanism of cerebral hypoxic‐ischemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Lactic acidosis and recovery of neuronal function following cerebral hypoxia in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Cell damage in the brain: a speculative synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Ion homeostasis in rat brain in vivo: intra- and extracellular [Ca2+] and [H+] in the hippocampus during recovery from short-term, transient ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Effects of lactacidosis on glial cell volume and viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Glutamate release and spreading depression in the fascia dentata in response to microdialysis with high K+: role of glia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Extracellular pH modulates N-methyl-D-aspartate receptor-mediated neurotoxicity and calcium accumulation in rat cortical cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Mechanistic distinctions between excitotoxic and acidotic hippocampal damage in an in vitro model of ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Mild acidosis protects hippocampal neurons from injury induced by oxygen and glucose deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Regional cerebral glucose metabolic rate during thirty minutes hypoxia of 7% oxygen in adult conscious rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Glucose, lactic acid, and perinatal hypoxic-ischemic brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Hyperglycemic versus normoglycemic stroke: topography of brain metabolites, intracellular pH, and infarct size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Brain lactic acidosis and synaptic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Resistance of astrocyte electrical membrane properties to acidosis changes in the presence of lactate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Effect of glucose on recovery of energy metabolism following hypoxia-oligemia in mouse brain: dose-dependence and carbohydrate specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Effects of hyperglycemia on the time course of changes in energy metabolism and pH during global cerebral ischemia and reperfusion in rats: correlation of 1H and 31P NMR spectroscopy with fatty acid and excitatory amino acid levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

Hyperglycemia decreases acute neuronal ischemic changes after middle cerebral artery occlusion in cats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.1993.TB03589.X

10.1111/J.1471-4159.1993.TB03589.X

21 January 2018

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

8360684