Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis. (Q40841876)

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2 November 2019

title

Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis (English)

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2 November 2019

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1

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2 November 2019

author name string

G Korbutt

2

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2 November 2019

M J Pinkoski

3

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2 November 2019

J A Heibein

4

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2 November 2019

A Caputo

5

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2 November 2019

M Hobman

6

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2 November 2019

M Barry

7

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2 November 2019

I Shostak

8

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2 November 2019

T Sawchuk

9

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2 November 2019

C F Holmes

10

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2 November 2019

J Gauldie

11

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R C Bleackley

12

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2 November 2019

language of work or name

English

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publication date

1 October 2000

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2 November 2019

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2 November 2019

volume

103

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2 November 2019

issue

3

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2 November 2019

page(s)

491-500

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Comparison of the human versus murine cytomegalovirus immediate early gene promoters for transgene expression by adenoviral vectors

2 November 2019

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The mannose 6-phosphate/insulin-like growth factor II receptor is a nanomolar affinity receptor for glycosylated human leukemia inhibitory factor.

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Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

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Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas

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Insulin-like growth factors (IGFs) stimulate the release of alpha 1-antichymotrypsin and soluble IGF-II/mannose 6-phosphate receptor from MCF7 breast cancer cells

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Insulin-like growth factor II/cation-independent mannose 6-phosphate receptor and lysosomal enzyme recognition

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

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Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation

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M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity

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Purified perforin induces target cell lysis but not DNA fragmentation

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Cell- and ligand-specific dephosphorylation of acid hydrolases: evidence that the mannose 6-phosphatase is controlled by compartmentalization

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New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

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Identification and characterization of cells deficient in the mannose 6-phosphate receptor: evidence for an alternate pathway for lysosomal enzyme targeting

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Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor

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Mechanism of lymphocyte-mediated cytotoxicity

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Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

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Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

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Interactions of recombinant and platelet transforming growth factor-beta 1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor

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Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

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Function of the two mannose 6-phosphate receptors in lysosomal enzyme transport

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Soluble Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor Carries Multiple High Molecular Weight Forms of Insulin-like Growth Factor II in Fetal Bovine Serum

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Suicidal tendencies: apoptotic cell death by caspase family proteinases

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Identifiers

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2 November 2019

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