Peptidomimetic design (Q40843326)

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Language	Label	Description	Also known as
English	Peptidomimetic design	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

24 September 2017

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Europe PubMed Central

Peptidomimetic design (English)

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Europe PubMed Central

24 September 2017

author name string

Ripka AS

1

1 reference

Europe PubMed Central

24 September 2017

Rich DH

2

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Europe PubMed Central

24 September 2017

publication date

1 August 1998

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Europe PubMed Central

24 September 2017

Current Opinion in Chemical Biology

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Europe PubMed Central

24 September 2017

2

1 reference

Europe PubMed Central

24 September 2017

4

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Europe PubMed Central

24 September 2017

441-452

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Europe PubMed Central

24 September 2017

Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design

1 reference

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The "One-Bead-One-Compound" Combinatorial Library Method

1 reference

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Modern computational chemistry and drug discovery: structure generating programs

1 reference

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Potent new inhibitors of human renin

1 reference

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Peptidomimetics derived from natural products

1 reference

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Locating ligand-binding sites in 7TM receptors by protein engineering.

1 reference

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Design of potent and selective human cathepsin K inhibitors that span the active site

1 reference

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Crystal structure of human cathepsin K complexed with a potent inhibitor

1 reference

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Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor

1 reference

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First examples of peptidomimetic inhibitors of interleukin-1 beta converting enzyme

1 reference

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Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors

1 reference

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Ureido-based peptidomimetic inhibitor of herpes simplex virus ribonucleotide reductase: an investigation of inhibitor bioactive conformation.

1 reference

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Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase with improved in vivo antiviral activity

1 reference

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Design, synthesis, and in vitro activities of benzamide-core glycoprotein IIb/IIIa antagonists: 2,3-diaminopropionic acid derivatives as surrogates of aspartic acid

1 reference

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Non-peptide RGD surrogates which mimic a Gly-Asp beta-turn: potent antagonists of platelet glycoprotein IIb-IIIa

1 reference

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From peptide to non-peptide. 3. Atropisomeric GPIIbIIIa antagonists containing the 3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione nucleus

1 reference

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Nonpeptide glycoprotein IIb/IIIa inhibitors: substituted quinazolinediones and quinazolinones as potent fibrinogen receptor antagonists

1 reference

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Rational design and synthesis of novel, potent bis-phenylamidine carboxylate factor Xa inhibitors

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Dibasic (Amidinoaryl)propanoic Acid Derivatives as Novel Blood Coagulation Factor Xa Inhibitors

1 reference

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X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition

1 reference

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Identification and initial structure-activity relationships of a novel class of nonpeptide inhibitors of blood coagulation factor Xa

1 reference

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Discovery and development of the novel potent orally active thrombin inhibitor N-(9-hydroxy-9-fluorenecarboxy)prolyl trans-4-aminocyclohexylmethyl amide (L-372,460): coapplication of structure-based design and rapid multiple analogue synthesis on so

1 reference

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7 January 2021

based on heuristic

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Design of highly potent noncovalent thrombin inhibitors that utilize a novel lipophilic binding pocket in the thrombin active site

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2898%2980119-1

7 January 2021

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The crystal structure of human alpha-thrombin complexed with LY178550, a nonpeptidyl, active site-directed inhibitor

1 reference

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7 January 2021

based on heuristic

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Amidino-substituted aromatic heterocycles as probes of the specificity pocket of trypsin-like proteases

1 reference

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Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2898%2980119-1

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Design and synthesis of potent and highly selective thrombin inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2898%2980119-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two thrombin-inhibitor complexes

1 reference

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Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease

1 reference

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Synthesis of 5,6-dihydro-4-hydroxy-2-pyrones as HIV-1 protease inhibitors: the profound effect of polarity on antiviral activity

1 reference

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Ras farnesyltransferase: a new therapeutic target

1 reference

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Farnesyltransferase as a target for anticancer drug design

1 reference

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based on heuristic

inferred from DOI database lookup

Potent, cell active, non-thiol tetrapeptide inhibitors of farnesyltransferase.

1 reference

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Discovery of novel nonpeptide tricyclic inhibitors of Ras farnesyl protein transferase

1 reference

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Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells

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Matrix metalloproteinase inhibitors in arthritis.

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Identifiers

10.1016/S1367-5931(98)80119-1

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

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