Prohormone and proneuropeptide processing. Recent progress and future challenges (Q40851194)

24 September 2017

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title

Prohormone and proneuropeptide processing. Recent progress and future challenges (English)

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24 September 2017

Beinfeld MC

1

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24 September 2017

1 February 1998

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24 September 2017

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24 September 2017

8

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24 September 2017

1

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24 September 2017

1-5

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https://scigraph.springernature.com/pub.10.1385/endo:8:1:1

24 September 2017

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cites work

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

1 reference

12 December 2020

Production of pro-opiomelanocortin (POMC) by a vaccinia virus transient expression system and in vitro processing of the expressed prohormone by POMC-converting enzyme

1 reference

12 December 2020

A novel member, PC7, of the mammalian kexin-like protease family: homology to PACE4A, its brain-specific expression and identification of isoforms

1 reference

12 December 2020

Differences in pH optima and calcium requirements for maturation of the prohormone convertases PC2 and PC3 indicates different intracellular locations for these events.

1 reference

12 December 2020

N-arginine dibasic convertase, a metalloendopeptidase as a prototype of a class of processing enzymes

1 reference

12 December 2020

CCK mRNA expression, pro-CCK processing, and regulated secretion of immunoreactive CCK peptides by rat insulinoma (RIN 5F) and mouse pituitary tumor (AtT-20) cells in culture

1 reference

12 December 2020

Vesicle fusion from yeast to man

1 reference

12 December 2020

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

1 reference

12 December 2020

cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells.

1 reference

12 December 2020

Purification and enzymatic characterization of recombinant prohormone convertase 2: stabilization of activity by 21 kDa 7B2

1 reference

12 December 2020

Hormone-producing cultures of adrenal and pituitary tumor origin

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12 December 2020

Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells

1 reference

12 December 2020

Role of PC2 in proenkephalin processing: antisense and overexpression studies.

1 reference

12 December 2020

Chromogranin A processing and secretion: specific role of endogenous and exogenous prohormone convertases in the regulated secretory pathway

1 reference

12 December 2020

Cholecystokinin (CCK) levels are greatly reduced in the brains but not the duodenums of Cpe(fat)/Cpe(fat) mice: a regional difference in the involvement of carboxypeptidase E (Cpe) in pro-CCK processing

1 reference

12 December 2020

Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease. Its testis-specific expression.

1 reference

12 December 2020

Processing of proTRH to its intermediate products occurs before the packing into secretory granules of transfected AtT20 cells

1 reference

12 December 2020

Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor

1 reference

12 December 2020

Processing of proendothelin-1 by human furin convertase

1 reference

12 December 2020

Cellular localization of the prohormone convertases in the hypothalamic paraventricular and supraoptic nuclei: selective regulation of PC1 in corticotrophin-releasing hormone parvocellular neurons mediated by glucocorticoids

1 reference

12 December 2020

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

1 reference

12 December 2020

Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms. Cleavage at a single arginine residue

1 reference

12 December 2020

Furin/PACE/SPC1: a convertase involved in exocytic and endocytic processing of precursor proteins

1 reference

12 December 2020

Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases

1 reference

12 December 2020

Cleavage of CCK 33 by recombinant PC2 in vitro

1 reference

12 December 2020

Pro-thyrotropin-releasing hormone processing by recombinant PC1

1 reference

12 December 2020

Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.

1 reference

12 December 2020

The synaptic vesicle cycle: a cascade of protein-protein interactions

1 reference

12 December 2020

The processing proteases prohormone thiol protease, PC1/3 and PC2, and 70-kDa aspartic proteinase show preferences among proenkephalin, proneuropeptide Y, and proopiomelanocortin substrates

1 reference

12 December 2020

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

1 reference

12 December 2020

Peptidylglycine alpha-amidating monooxygenase: a multifunctional protein with catalytic, processing, and routing domains

1 reference

12 December 2020

Tissue distribution of a dynorphin-processing endopeptidase.

1 reference

12 December 2020

Cleavage of recombinant enkephalin precursor by endoproteolytic activity in bovine chromaffin granules

1 reference

12 December 2020

Immunological identification and localization of yeast aspartic protease 3-like prohormone-processing enzymes in mammalian brain and pituitary.

1 reference

12 December 2020

Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

1 reference

12 December 2020

Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus

1 reference

12 December 2020

Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2.

1 reference

12 December 2020

Effect of carboxypeptidase E deficiency on progastrin processing and gastrin messenger ribonucleic acid expression in mice with the fat mutation

1 reference

12 December 2020

Heterologous processing of prosomatostatin in constitutive and regulated secretory pathways. Putative role of the endoproteases furin, PC1, and PC2

1 reference

12 December 2020

Prohormone convertase 2 is necessary for the formation of cholecystokinin-22, but not cholecystokinin-8, in RIN5F and STC-1 cells

1 reference

12 December 2020

Prohormone convertase 1 is necessary for the formation of cholecystokinin 8 in Rin5F and STC-1 cells

1 reference

12 December 2020

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

1 reference

12 December 2020

Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease.

1 reference

12 December 2020

Proneuropeptide Y processing in large dense-core vesicles: manipulation of prohormone convertase expression in sympathetic neurons using adenoviruses

1 reference

12 December 2020

Expression of rat pro cholecystokinin (CCK) in bacteria and in insect cells infected with recombinant baculovirus.

1 reference

12 December 2020

Identification of a Second Human Subtilisin-Like Protease Gene in thefes/fpsRegion of Chromosome 15

1 reference

12 December 2020

Gene expression of prohormone and proprotein convertases in the rat CNS: a comparative in situ hybridization analysis.

1 reference

12 December 2020

Specificity and kinetic studies on the cleavage of various prohormone mono- and paired-basic residue sites by yeast aspartic protease 3.

1 reference

12 December 2020

Specificity of prohormone convertase endoproteolysis of progastrin in AtT-20 cells

1 reference

12 December 2020

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

1 reference

12 December 2020

Expression of PC3, carboxypeptidase E and enkephalin in human monocyte-derived macrophages as a tool for genetic studies

1 reference

12 December 2020

Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases.

1 reference

12 December 2020

Expression of antisense PC1 in stably transfected RIN5F cells significantly reduces CCK 8 biosynthesis

1 reference

12 December 2020

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

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12 December 2020

Purification and characterization of the prohormone convertase PC1(PC3)

1 reference

12 December 2020

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

1 reference

12 December 2020

Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site

1 reference

12 December 2020

Evidence for an endogenous cholecystokininergic balance in social memory

1 reference

12 December 2020

Identifiers

DOI

10.1385/ENDO:8:1:1

1 reference

PubMed ID

9666338

Dimensions Publication ID

24 September 2017

1036309866

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Fatcat ID

release_4bvyjhvqsrggzi47sl67vm4xi4

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Fatcat

https://api.fatcat.wiki/v0/release/4bvyjhvqsrggzi47sl67vm4xi4

24 November 2022

mapped directly with Wikidata item

PubMed ID

9666338

1 reference

PubMed ID

9666338