Leukemic cell line, KG-1 has a functional loss of hOGG1 enzyme due to a point mutation and 8-hydroxydeoxyguanosine can kill KG-1. (Q40852916)

24 September 2017

Leukemic cell line, KG-1 has a functional loss of hOGG1 enzyme due to a point mutation and 8-hydroxydeoxyguanosine can kill KG-1. (English)

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24 September 2017

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Hyun JW

1

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24 September 2017

Choi JY

2

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24 September 2017

Zeng HH

3

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24 September 2017

Lee YS

4

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24 September 2017

Kim HS

5

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24 September 2017

Yoon SH

6

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24 September 2017

Chung MH

7

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24 September 2017

language of work or name

English

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publication date

1 September 2000

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24 September 2017

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24 September 2017

19

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39

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24 September 2017

4476-4479

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203787

24 September 2017

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cites work

Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

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Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine

21 January 2018

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Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

21 January 2018

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Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours.

21 January 2018

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Thermolabile 8-hydroxyguanine DNA glycosylase with low activity in senescence-accelerated mice due to a single-base mutation.

21 January 2018

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An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA.

21 January 2018

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Excision of oxidatively damaged DNA bases by the human alpha-hOgg1 protein and the polymorphic alpha-hOgg1(Ser326Cys) protein which is frequently found in human populations

21 January 2018

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Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair.

21 January 2018

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Induction of E. coli oh8Gua endonuclease by oxidative stress: its significance in aerobic life.

21 January 2018

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Genetic polymorphisms and alternative splicing of the hOGG1 gene, that is involved in the repair of 8-hydroxyguanine in damaged DNA.

21 January 2018

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Identification of 8-hydroxyguanine glycosylase activity in mammalian tissues using 8-hydroxyguanine specific monoclonal antibody.

21 January 2018

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A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer

21 January 2018

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Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily

21 January 2018

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Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae

21 January 2018

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Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase

21 January 2018

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Infrequent mutations of the hOGG1 gene, that is involved in the excision of 8-hydroxyguanine in damaged DNA, in human gastric cancer

21 January 2018

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Measurement of protein using bicinchoninic acid

21 January 2018

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8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity

21 January 2018

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3′-End labeling of DNA with [α-32P] cordycepin-5′-triphosphate

21 January 2018

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Ubiquitous presence in mammalian cells of enzymatic activity specifically cleaving 8-hydroxyguanine-containing DNA

21 January 2018

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An endonuclease activity in human polymorphonuclear neutrophils that removes 8-hydroxyguanine residues from DNA+

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Generation and elimination of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate, a mutagenic substrate for DNA synthesis, in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203787

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1203787

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Dimensions Publication ID

24 September 2017

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