Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means (Q40859254)

24 September 2017

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title

Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means (English)

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24 September 2017

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2

Neuwelt EA

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24 September 2017

Kroll RA

1

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PubMed ID

9588554

24 September 2017

language of work or name

English

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publication date

1 May 1998

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24 September 2017

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24 September 2017

42

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24 September 2017

5

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24 September 2017

1083-99; discussion 1099-100

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Transporting therapeutics across the blood-brain barrier

24 September 2017

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Convection-enhanced delivery of macromolecules in the brain

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The safety of interstitial chemotherapy with BCNU-loaded polymer followed by radiation therapy in the treatment of newly diagnosed malignant gliomas: phase I trial

21 January 2018

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Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group

21 January 2018

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The distribution within the brain of ferritin injected into cerebrospinal fluid compartments. I. Ependymal distribution

21 January 2018

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Osmotic opening of tight junctions in cerebral endothelium

21 January 2018

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Experimental study of contrast media for cerebral angiography with reference to possible injurious effects on the cerebral blood vessels.

21 January 2018

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Boronated epidermal growth factor as a potential targeting agent for boron neutron capture therapy of brain tumors

21 January 2018

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Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy

21 January 2018

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Hyperosmotic modulation of the cytosolic calcium concentration in a rat osteoblast-like cell line

21 January 2018

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Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption.

21 January 2018

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Pilot study of high-dose thiotepa and etoposide with autologous bone marrow rescue in children and young adults with recurrent CNS tumors. The Children's Cancer Group.

21 January 2018

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Antisense oligonucleotides for central nervous system tumors

21 January 2018

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Preirradiation chemotherapy with carboplatin and etoposide in newly diagnosed embryonal pediatric CNS tumors

21 January 2018

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Brain drug delivery of small molecules using immunoliposomes

21 January 2018

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Bradykinin selectively opens blood-tumor barrier in experimental brain tumors.

21 January 2018

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Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors

21 January 2018

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The ultrastructural basis of capillary permeability studied with peroxidase as a tracer

21 January 2018

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Efficacy of direct intratumoral therapy with targeted protein toxins for solid human gliomas in nude mice.

21 January 2018

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Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7.

21 January 2018

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A new model of systemic drug rescue based on permeability characteristics of the blood-brain barrier in intracerebral abscess-bearing rats.

21 January 2018

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Effect of osmotic blood-brain barrier disruption on methotrexate pharmacokinetics in the dog.

21 January 2018

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Characterization of a new model of GM2-gangliosidosis (Sandhoff's disease) in Korat cats

21 January 2018

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Increased delivery of tumor-specific monoclonal antibodies to brain after osmotic blood-brain barrier modification in patients with melanoma metastatic to the central nervous system.

21 January 2018

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Delivery of virus-sized iron oxide particles to rodent CNS neurons

21 January 2018

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Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption

21 January 2018

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Intracarotid infusion of bradykinin selectively increases blood-tumor permeability in 9L and C6 brain tumors.

21 January 2018

1 reference

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Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

21 January 2018

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Brain-targeted delivery of a leucine-enkephalin analogue by retrometabolic design.

21 January 2018

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Tight-junctional modification as the basis of osmotic opening of the blood-brain barrier.

21 January 2018

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Long-term toxicity and neuropathology associated with the sequencing of cranial irradiation and enhanced chemotherapy delivery.

21 January 2018

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Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms.

21 January 2018

1 reference

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Enhanced delivery of boronophenylalanine for neutron capture therapy by means of intracarotid injection and blood-brain barrier disruption.

21 January 2018

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Quantification and pharmacokinetics of blood-brain barrier disruption in humans

21 January 2018

1 reference

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Hyperosmolar blood-brain barrier disruption in baboons: an in vivo study using positron emission tomography and rubidium-82.

21 January 2018

1 reference

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10.1097/00006123-199805000-00082

21 January 2018

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

9588554