Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor (Q40864660)

24 September 2017

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title

Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor (English)

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24 September 2017

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J C Meunier

1

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PubMed ID

9527501

24 September 2017

language of work or name

English

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publication date

1 December 1997

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European Journal of Pharmacology

24 September 2017

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24 September 2017

340

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24 September 2017

1-15

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24 September 2017

1

1 reference

Determination of activity for nociceptin in the mouse vas deferens

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

The mouse vas deferens: a pharmacological preparation sensitive to nociceptin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin, an endogenous ligand for the ORL1 receptor, has novel hypotensive activity in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Specific receptor for the opioid peptide dynorphin: structure--activity relationships

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

The effect of nociceptin on Ca2+ channel current and intracellular Ca2+ in the SH-SY5Y human neuroblastoma cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin (Orphanin FQ) abolishes gestational and ovarian sex steroid-induced antinociception and induces hyperalgesia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

The novel neuropeptide orphanin FQ fails to produce conditioned place preference or aversion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Orphanin FQ: receptor binding and analog structure activity relationships in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Depression of glutamatergic transmission by nociceptin in the neonatal rat hemisected spinal cord preparation in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin stimulates locomotion and exploratory behaviour in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Na+ ions and Gpp(NH)p selectively inhibit agonist interactions at mu- and kappa-opioid receptor sites in rabbit and guinea-pig cerebellum membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

cDNA cloning and regional distribution of a novel member of the opioid receptor family.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Modulation of enkephalin release by nociceptin (orphanin FQ).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Inhibition of tachykinin release from peripheral endings of sensory nerves by nociceptin, a novel opioid peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin: an endogenous agonist for central opioid like1 (ORL1) receptors possesses systemic vasorelaxant properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Functional role and sequence analysis of a lymphocyte orphan opioid receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Lack of cross-tolerance between the antinociceptive effect of intrathecal orphanin FQ and morphine in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Structure and regional distribution of nociceptin/orphanin FQ precursor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Functional coupling of the nociceptin/orphanin FQ receptor with the G-protein-activated K+ (GIRK) channel.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Home for an orphan endorphin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Pronociceptive effects of the neuropeptide, nociceptin, in the land snail, Cepaea nemoralis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Spinal analgesic activity of orphanin FQ/nociceptin and its fragments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Effects of sigma ligands on the nociceptin/orphanin FQ receptor co-expressed with the G-protein-activated K+ channel in Xenopus oocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Selective amplification and cloning of four new members of the G protein-coupled receptor family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Functional expression, activation and desensitization of opioid receptor-like receptor ORL1 in neuroblastoma x glioma NG108-15 hybrid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Biochemical evidence for orphanin FQ/nociceptin receptor heterogeneity in mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Moving from the orphanin FQ receptor to an opioid receptor using four point mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Orphanin FQ is a functional anti-opioid peptide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Replacement of Gln280 by His in TM6 of the human ORL1 receptor increases affinity but reduces intrinsic activity of opioids.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Opioid modulation of appetite

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Inhibition by nociceptin of the light-evoked release of ACh from retinal cholinergic neurones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin induced inhibition of K+ evoked glutamate release from rat cerebrocortical slices

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Structure and chromosomal mapping of genes for the mouse kappa-opioid receptor and an opioid receptor homologue (MOR-C).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Association of aminopeptidase N and endopeptidase 24.15 inhibitors potentiate behavioral effects mediated by nociceptin/orphanin FQ in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Primary structure and tissue distribution of the orphanin FQ precursor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Identification and characterization of an endogenous ligand for opioid receptor homologue ROR-C: its involvement in allodynic response to innocuous stimulus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Cloning and expression of a cDNA encoding a mouse brain orphanin FQ/nociceptin precursor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Neuropeptide FF, a mammalian neuropeptide with multiple functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Structure-activity relationship studies on the novel neuropeptide orphanin FQ.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Naloxone sensitive orphanin FQ-induced analgesia in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Excitement over orphanin FQ/nociceptin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Molecular Cloning and Characterization of a Novel Form of Neuropeptide Gene as a Developmentally Regulated Molecule

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Solution conformation of nociceptin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Molecular pharmacology of the opioid receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Determination of nociceptin-like immunoreactivity in the rat dorsal spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin/orphanin FQ and opioid peptides show overlapping distribution but not co-localization in pain-modulatory brain regions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

ACTH: a short introductory review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Sensitivity of opioid receptor-like receptor ORL1 for chemical modification on nociceptin, a naturally occurring nociceptive peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Identification of opioid receptor-like (ORL1) peptide-stimulated [35S]GTP gamma S binding in rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

The molecular basis of opioid receptor function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Inhibitory action of nociceptin on spinal dorsal horn neurones of the rat, in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Injections of nociceptin into nucleus accumbens shell or ventromedial hypothalamic nucleus increase food intake.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Increase by the ORL1 receptor (opioid receptor-like1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Actions of the ORL1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nonopiate effects of dynorphin and des-Tyr-dynorphin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

cDNA cloning of an orphan opiate receptor gene family member and its splice variant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin (orphanin FQ), an endogenous ligand for the QRL1 (opioid-receptor-like1) receptor; modulates responses of trigeminal neurons evoked by excitatory amino acids and somatosensory stimuli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned mu, delta, and kappa opioid receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Effects of intrathecally administered nociceptin, an opioid receptor-like1 (ORL1) receptor agonist, on the thermal hyperalgesia induced by unilateral constriction injury to the sciatic nerve in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Effects of intrathecally administered nociceptin, an opioid receptor-like1 (ORL1) receptor agonist, on the thermal hyperalgesia induced by carageenan injection into the rat paw.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Nociceptin in vitro biotransformation in human blood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Identification of dynorphins as endogenous ligands for an opioid receptor-like orphan receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

Demonstration of kappa 3-opioid receptors in the SH-SY5Y human neuroblastoma cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2897%2901411-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-2999(97)01411-8

1 reference

24 September 2017

1 reference

PubMed ID

9527501