Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR. (Q40871190)

24 September 2017

Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR. (English)

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24 September 2017

Kim SH

1

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24 September 2017

Forman AP

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2

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24 September 2017

Mathews MB

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3

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24 September 2017

Gunnery S

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4

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24 September 2017

language of work or name

English

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publication date

1 June 2000

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24 September 2017

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24 September 2017

19

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24 September 2017

3086-3094

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24 September 2017

27

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203632

24 September 2017

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cites work

Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

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Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

21 January 2018

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The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties

21 January 2018

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Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.

21 January 2018

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The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR

21 January 2018

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The double-stranded RNA-dependent protein kinase PKR: structure and function

21 January 2018

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A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

21 January 2018

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Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression

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RNA binding and modulation of PKR activity.

21 January 2018

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The interferon system: a review with emphasis on the role of PKR in growth control

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Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

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Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA-dependent protein kinase, PKR

21 January 2018

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The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins

21 January 2018

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Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

21 January 2018

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Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction

21 January 2018

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Activation of the double-stranded-RNA-activated protein kinase and induction of vascular cell adhesion molecule-1 by poly (I).poly (C) in endothelial cells.

21 January 2018

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DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR

21 January 2018

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eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange.

21 January 2018

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The P58 cellular inhibitor complexes with the interferon-induced, double-stranded RNA-dependent protein kinase, PKR, to regulate its autophosphorylation and activity

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Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA.

21 January 2018

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Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2

21 January 2018

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Use of vertical slab isoelectric focusing and immunoblotting to evaluate steady-state phosphorylation of eIF2 alpha in cultured cells

21 January 2018

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Inhibition of double-stranded RNA- and tumor necrosis factor alpha-mediated apoptosis by tetratricopeptide repeat protein and cochaperone P58(IPK)

21 January 2018

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Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation

21 January 2018

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Tumor suppressor p53 as a component of the tumor necrosis factor-induced, protein kinase PKR-mediated apoptotic pathway in human promonocytic U937 cells

21 January 2018

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Blockage of NF-kappa B signaling by selective ablation of an mRNA target by 2-5A antisense chimeras

21 January 2018

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Cell cycle regulation of the double stranded RNA activated protein kinase, PKR

21 January 2018

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Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells.

21 January 2018

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7 January 2021

Expression of the double-stranded RNA-dependent protein kinase (p68) in human breast tissues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203632

7 January 2021

Interferon-responsive protein kinase (p68) and proliferating cell nuclear antigen are inversely distributed in head and neck squamous cell carcinoma

1 reference

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7 January 2021

The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203632

7 January 2021

Use of monoclonal antibodies to study the structure and function of eukaryotic protein synthesis initiation factor eIF-2B

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203632

7 January 2021

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203632

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203632

1 reference

Dimensions Publication ID

24 September 2017

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1 reference