DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling (Q40871212)

24 September 2017

title

DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling (English)

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24 September 2017

Tee AR

1

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24 September 2017

Proud CG

series ordinal

2

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24 September 2017

language of work or name

English

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publication date

1 June 2000

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24 September 2017

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24 September 2017

volume

19

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24 September 2017

issue

26

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24 September 2017

page(s)

3021-3031

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203622

24 September 2017

exact match

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cites work

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

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Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

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Translational control: the cancer connection

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Effect of brain ischemia and reperfusion on the localization of phosphorylated eukaryotic initiation factor 2 alpha

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Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

21 January 2018

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Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression

21 January 2018

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Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation

21 January 2018

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Induction of apoptosis by double-stranded-RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB.

21 January 2018

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4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

21 January 2018

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

21 January 2018

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

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Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family

21 January 2018

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Rapamycin potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid cells

21 January 2018

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PKR, apoptosis and cancer

21 January 2018

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Rapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: evidence for the possible involvement of FK506-binding protein 25

21 January 2018

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Phosphorylation of the eIF4E-binding protein PHAS-I after exposure of PC12 cells to EGF and NGF.

21 January 2018

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Regulation of translation initiation factors by signal transduction

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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PHAS/4E-BPs as regulators of mRNA translation and cell proliferation

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins

21 January 2018

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Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells

21 January 2018

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Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells.

21 January 2018

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Bidirectional modulation of insulin action by amino acids

21 January 2018

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Molecular mechanisms for the control of translation by insulin

21 January 2018

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Insulin receptor substrate-4 enhances insulin-like growth factor-I-induced cell proliferation

21 January 2018

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Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

21 January 2018

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Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

21 January 2018

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Caspase-mediated cleavage of eukaryotic translation initiation factor subunit 2alpha

21 January 2018

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Inactivation of eIF2B and phosphorylation of PHAS-I in heat-shocked rat hepatoma cells

21 January 2018

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Photocrosslinking locates a binding site for the large subunit of human replication protein A to the damaged strand of cisplatin-modified DNA

21 January 2018

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Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

21 January 2018

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Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

21 January 2018

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Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

Double-stranded RNA-activated protein kinase (PKR) fused to green fluorescent protein induces apoptosis of human embryonic kidney cells: possible role in the Fas signaling pathway.

21 January 2018

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TOR signalling and control of cell growth

21 January 2018

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Amino acid availability regulates p70 S6 kinase and multiple translation factors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

Regulation of protein synthesis in Swiss 3T3 fibroblasts. Rapid activation of the guanine-nucleotide-exchange factor by insulin and growth factors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

p70s6k function is essential for G1 progression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

7 January 2021

Caspase-3 is necessary and sufficient for cleavage of protein synthesis eukaryotic initiation factor 4G during apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

7 January 2021

Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

7 January 2021

The type I angiotensin II receptor couples to Stat1 and Stat3 activation through Jak2 kinase in neonatal rat cardiac myocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

7 January 2021

Cleavage of translation initiation factor 4G (eIF4G) during anti-Fas IgM-induced apoptosis does not require signalling through the p38 mitogen-activated protein (MAP) kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

7 January 2021

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

7 January 2021

Heat shock increases the association of binding protein-1 with initiation factor 4E

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203622

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203622

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Dimensions Publication ID

24 September 2017

1010989642

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1 reference