Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C. (Q40874259)

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23 October 2019

title

Increased Kit/SCF receptor induced mitogenicity but abolished cell motility after inhibition of protein kinase C (English)

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23 October 2019

5

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23 October 2019

author name string

P Blume-Jensen

1

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23 October 2019

A Siegbahn

2

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23 October 2019

S Stabel

3

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23 October 2019

C H Heldin

4

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23 October 2019

language of work or name

English

0 references

publication date

1 November 1993

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23 October 2019

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23 October 2019

volume

12

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23 October 2019

issue

11

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23 October 2019

page(s)

4199-4209

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Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

23 October 2019

cites work

1 reference

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A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

24 September 2017

1 reference

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Steel factor and c-kit receptor: from mutants to a growth factor system

24 September 2017

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Analysis of pleiotropism at the dominant white-spotting (W) locus of the house mouse: a description of ten new W alleles

24 September 2017

1 reference

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The molecular heterogeneity of protein kinase C and its implications for cellular regulation

24 September 2017

1 reference

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The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

24 September 2017

1 reference

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Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

24 September 2017

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Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand

24 September 2017

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Colony-stimulating factor 1 activates protein kinase C in human monocytes

24 September 2017

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Signal transduction by receptors with tyrosine kinase activity

24 September 2017

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B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase

24 September 2017

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Signaling through phosphatidylcholine breakdown.

24 September 2017

1 reference

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Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

24 September 2017

1 reference

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Domain interactions in protein kinase C

24 September 2017

1 reference

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The kit ligand encoded at the murine Steel locus: a pleiotropic growth and differentiation factor

24 September 2017

1 reference

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Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

24 September 2017

1 reference

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Comparative analysis of signaling pathways between mast cell growth factor (c-kit ligand) and granulocyte-macrophage colony-stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of Raf-1, GTPase-activating [...]

24 September 2017

1 reference

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Deletion of the c-kit protooncogene in the human developmental defect piebald trait

24 September 2017

1 reference

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Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase

24 September 2017

1 reference

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In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: two distinct waves of c-kit-dependency during melanocyte development.

24 September 2017

1 reference

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The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.

24 September 2017

1 reference

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SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

24 September 2017

1 reference

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A specific combination of substrates is involved in signal transduction by the kit-encoded receptor.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W

24 September 2017

1 reference

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

24 September 2017

1 reference

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

24 September 2017

1 reference

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The role of protein kinase C in insulin action

24 September 2017

1 reference

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Signal transduction system for growth factor receptors associated with tyrosine kinase activity: epidermal growth factor receptor signalling and its regulation.

24 September 2017

1 reference

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MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin

24 September 2017

1 reference

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Protein kinase C isozymes have distinct roles in neural induction and competence in Xenopus

24 September 2017

1 reference

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Molecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylation

24 September 2017

1 reference

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The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation

24 September 2017

1 reference

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Protein kinase C, calcium and phospholipid degradation

24 September 2017

1 reference

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Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction

24 September 2017

1 reference

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The MARCKS brothers: a family of protein kinase C substrates

24 September 2017

1 reference

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The protein kinase C family

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Dominant negative and loss of function mutations of the c-kit (mast/stem cell growth factor receptor) proto-oncogene in human piebaldism

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Hereditary anemias of the mouse: a review for geneticists

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Interaction of epidermal growth factor-dependent protein kinase with endogenous membrane proteins and soluble peptide substrate

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Purification of the receptor for platelet-derived growth factor from porcine uterus

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family.

15 June 2018

1 reference

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Receptor-ligand interaction: a new method for determining binding parameters without a priori assumptions on non-specific binding

15 June 2018

1 reference

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Acid and base hydrolysis of phosphoproteins bound to immobilon facilitates analysis of phosphoamino acids in gel-fractionated proteins.

15 June 2018

1 reference

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Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor.

15 June 2018

1 reference

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Characterization of the platelet-derived growth factor beta-receptor kinase activity by use of synthetic peptides

15 June 2018

1 reference

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Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis

15 June 2018

1 reference

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Protein kinase-c activation inhibits tyrosine phosphorylation of the c-met protein

15 June 2018

1 reference

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Expression of protein kinase C isotypes using baculovirus vectors.

15 June 2018

1 reference

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Role of c-kit in mouse spermatogenesis: identification of spermatogonia as a specific site of c-kit expression and function

15 June 2018

1 reference

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Substrate phosphorylation specificity of the human c-kit receptor tyrosine kinase

15 June 2018

1 reference

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Requirement for mast cell growth factor for primordial germ cell survival in culture

15 June 2018

1 reference

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Identification of multiple PKC isoforms in Swiss 3T3 cells: Differential down-regulation by phorbol ester

15 June 2018

1 reference

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Activation of the c-Raf protein kinase by protein kinase C phosphorylation

15 June 2018

1 reference

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TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Autophosphorylation and protein kinase C phosphorylation of the epidermal growth factor receptor. Effect on tyrosine kinase activity and ligand binding affinity

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413714

Haemopoietic stem cell development to neutrophils is associated with subcellular redistribution and differential expression of protein kinase C subspecies

2 December 2018

1 reference

12 December 2020

Immunocytochemical expression and localization of protein kinase C in bovine aortic endothelial cells

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12 December 2020

Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture

1 reference

12 December 2020

Diffusible factors in vertebrate embryonic induction

1 reference

12 December 2020

Effects of the steel gene product on mouse primordial germ cells in culture

1 reference

12 December 2020

Suppression of protein tyrosine kinase activity of the epidermal growth factor receptor by epidermal growth factor

1 reference

12 December 2020

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity

1 reference

12 December 2020

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C

1 reference

12 December 2020

EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling

1 reference

12 December 2020

Steel factor is required for maintenance, but not differentiation, of melanocyte precursors in the neural crest

1 reference

12 December 2020

Protein kinase C downregulation?

1 reference

12 December 2020

10.1002/J.1460-2075.1993.TB06104.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7693453%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7693453%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

1 reference