Long-term cultured IL-2-dependent T cell lines demonstrate p16(INK4a) overexpression, normal pRb/p53, and upregulation of cyclins E or D2. (Q40876849)

24 September 2017

Long-term cultured IL-2-dependent T cell lines demonstrate p16(INK4a) overexpression, normal pRb/p53, and upregulation of cyclins E or D2. (English)

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24 September 2017

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7

Roos G

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24 September 2017

Siwicki JK

1

1 reference

24 September 2017

Hedberg Y

2

1 reference

24 September 2017

Nowak R

3

1 reference

24 September 2017

Lodén M

4

1 reference

24 September 2017

Zhao J

5

1 reference

24 September 2017

Landberg G

6

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24 September 2017

1 May 2000

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24 September 2017

Experimental Gerontology

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24 September 2017

35

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24 September 2017

3

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24 September 2017

375-388

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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Gene amplification and overexpression of CDK4 in sporadic breast carcinomas is associated with high tumor cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Regulation of G1/S transition by cyclins D2 and D3 in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Mechanism of telomerase induction during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Frequent deregulation of p16 and the p16/G1 cell cycle-regulatory pathway in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Involvement of the Ink4 proteins p16 and p15 in T-lymphocyte senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Cyclin E, a redundant cyclin in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Telomeres shorten during ageing of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Cyclin E dependent kinase activity in human breast cancer in relation to cyclin E, p27 and p21 expression and retinoblastoma protein phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Bcl-2 modulates telomerase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Deregulation of cyclin E and D1 in breast cancer is associated with inactivation of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Telomeres and telomerase in normal and malignant haematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Changes in telomerase activity and telomere length during human T lymphocyte senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

T cell immunosenescence in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

The tumor suppressor protein p16INK4a.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Long-term growth of human WGA-activated T-lymphocytes without feeder cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Re-expression of endogenous p16ink4a in oral squamous cell carcinoma lines by 5-aza-2'-deoxycytidine treatment induces a senescence-like state

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Induction of senescence in human malignant glioma cells by p16INK4A.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Myc activates telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

A Detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Direct activation of TERT transcription by c-MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900088-7

7 January 2021

10.1016/S0531-5565(00)00088-7

Identifiers

DOI

1 reference

24 September 2017

1 reference