Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha (Q40881293)

24 September 2017

Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha (English)

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24 September 2017

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M P Pando

1

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PubMed ID

10801847

24 September 2017

I M Verma

series ordinal

2

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PubMed ID

10801847

24 September 2017

language of work or name

English

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publication date

1 July 2000

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Journal of Biological Chemistry

24 September 2017

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24 September 2017

275

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24 September 2017

21278-21286

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24 September 2017

28

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NF-kappa B: ten years after

24 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Function and activation of NF-kappa B in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

The NF-kappa B/Rel and I kappa B gene families: mediators of immune response and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Structure of an IkappaBalpha/NF-kappaB complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Identification and characterization of an IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Autoregulation of I kappa B alpha activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Constitutive phosphorylation of I kappa B alpha by casein kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

c-rel activates but v-rel suppresses transcription from kappa B sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002532200

21 January 2018

Identifiers

DOI

10.1074/JBC.M002532200

1 reference

24 September 2017

1 reference

PubMed ID

10801847