Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells (Q40882225)

24 September 2017

Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells (English)

1 reference

24 September 2017

Ram TG

1

1 reference

PubMed ID

10797304

24 September 2017

Hosick HL

series ordinal

2

1 reference

PubMed ID

10797304

24 September 2017

Ethier SP

series ordinal

3

1 reference

24 September 2017

1 June 2000

1 reference

Journal of Cellular Physiology

24 September 2017

1 reference

24 September 2017

183

1 reference

24 September 2017

3

1 reference

24 September 2017

301-313

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Growth factors and cancer

24 September 2017

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PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

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A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity

21 January 2018

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A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling

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Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

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Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

21 January 2018

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A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine

21 January 2018

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cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

21 January 2018

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Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

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Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members

21 January 2018

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Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

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Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract

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Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

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Identification of heregulin, a specific activator of p185erbB2

21 January 2018

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Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

21 January 2018

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Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

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Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors

21 January 2018

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SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

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p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin.

21 January 2018

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

21 January 2018

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Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

21 January 2018

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Heregulin induces tyrosine phosphorylation of HER4/p180erbB4

21 January 2018

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Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells

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Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine-phosphorylated p185erbB-2.

21 January 2018

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The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

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Gamma-heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175.

21 January 2018

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Deletion of the kinase insert sequence of the platelet-derived growth factor beta-receptor affects receptor kinase activity and signal transduction

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Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

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Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

21 January 2018

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ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

21 January 2018

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Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha

21 January 2018

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A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

21 January 2018

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Signal transduction by receptors with tyrosine kinase activity

21 January 2018

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Role of PI 3-kinase in mitogenesis

21 January 2018

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Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

21 January 2018

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Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

21 January 2018

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Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

21 January 2018

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10.1002/(SICI)1097-4652(200006)183:3<301::AID-JCP2>3.0.CO;2-W

21 January 2018

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

10797304