[(11)C]FMAU and [(18)F]FHPG as PET tracers for herpes simplex virus thymidine kinase enzyme activity and human cytomegalovirus infections (Q40885241)

24 September 2017

[(11)C]FMAU and [(18)F]FHPG as PET tracers for herpes simplex virus thymidine kinase enzyme activity and human cytomegalovirus infections (English)

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24 September 2017

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de Vries EF

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24 September 2017

van Waarde A

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24 September 2017

Harmsen MC

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24 September 2017

Mulder NH

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24 September 2017

Vaalburg W

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24 September 2017

Hospers GA

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24 September 2017

1 February 2000

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Nuclear Medicine and Biology

24 September 2017

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24 September 2017

27

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24 September 2017

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24 September 2017

113-119

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Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU) terminated by severe neurologic toxicity.

24 September 2017

1 reference

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7 January 2021

Synthesis and preliminary evaluation of 9-(4-[18F]-fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG): a new potential imaging agent for viral infection and gene therapy using PET.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2899%2900105-5

7 January 2021

9-[(3-[18F]-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG): a potential imaging agent of viral infection and gene therapy using PET.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2899%2900105-5

7 January 2021

Evaluation of 9-[(3-18F-fluoro-1-hydroxy-2-propoxy)methyl]guanine ([18F]-FHPG) in vitro and in vivo as a probe for PET imaging of gene incorporation and expression in tumors

1 reference

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7 January 2021

The thymidine kinase/ganciclovir-mediated "suicide" effect is variable in different tumor cells

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https://api.crossref.org/works/10.1016%2FS0969-8051%2899%2900105-5

7 January 2021

Differential activity of potential antiviral nucleoside analogs on herpes simplex virus-induced and human cellular thymidine kinases

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7 January 2021

Synthesis and biological effects of 2'-fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil

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https://api.crossref.org/works/10.1016%2FS0969-8051%2899%2900105-5

7 January 2021

Efficacy and selectivity of some nucleoside analogs as anti-human cytomegalovirus agents

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https://api.crossref.org/works/10.1016%2FS0969-8051%2899%2900105-5

7 January 2021

Synthesis of 2'-fluoro-5-[11C]-methyl-1-beta-D-arabinofuranosyluracil ([11C]-FMAU): a potential nucleoside analog for in vivo study of cellular proliferation with PET.

1 reference

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7 January 2021

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7 January 2021

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

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7 January 2021

Sequence and transcriptional analysis of the guinea pig cytomegalovirus UL97 homolog

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7 January 2021

Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography

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7 January 2021

Ultrastructural analysis of circulating cytomegalic cells in patients with active cytomegalovirus infection: evidence for virus production and endothelial origin

1 reference

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7 January 2021

Ganciclovir uptake in human mammary carcinoma cells expressing herpes simplex virus thymidine kinase

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7 January 2021

Enzymatic phosphorylation of acyclic nucleoside analogs and correlations with antiherpetic activities

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7 January 2021

Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues. A review

1 reference

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7 January 2021

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

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7 January 2021

Unique metabolism of a novel antiviral L-nucleoside analog, 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil: a substrate for both thymidine kinase and deoxycytidine kinase

1 reference

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7 January 2021

Ganciclovir permeation of the human erythrocyte membrane

1 reference

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7 January 2021

Development of a positron emission tomography radiopharmaceutical for imaging thymidine kinase gene expression: Synthesis and in vitro evaluation of 9-{3-[18F] Fluoro-1-hydroxy-2-propoxymethyl guanine

1 reference

https://api.crossref.org/works/10.1016%2FS0969-8051%2899%2900105-5

7 January 2021

Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors

1 reference

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7 January 2021

Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene.

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7 January 2021

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells.

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7 January 2021

The murine cytomegalovirus (MCMV) homolog of the HCMV phosphotransferase (UL97(pk)) gene.

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7 January 2021

Quantitative autoradiographic mapping of herpes simplex virus encephalitis with a radiolabeled antiviral drug

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7 January 2021

Fibroblasts, epithelial cells, endothelial cells and smooth muscle cells are major targets of human cytomegalovirus infection in lung and gastrointestinal tissues

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7 January 2021

Human cytomegalovirus cell tropism and pathogenesis

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7 January 2021

Quantification of replication of clinical cytomegalovirus isolates in cultured endothelial cells and fibroblasts by a focus expansion assay

1 reference

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7 January 2021

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

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7 January 2021

Characterization of rhesus cytomegalovirus genes associated with anti-viral susceptibility

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7 January 2021

The human cytomegalovirus UL97 protein is phosphorylated and a component of virions

1 reference

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7 January 2021

Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides

1 reference

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7 January 2021

19F NMR study of the uptake of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil in erythrocytes: evidence of transport by facilitated and nonfacilitated pathways.

1 reference

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7 January 2021

Phosphorylation of aciclovir, ganciclovir, penciclovir and S2242 by the cytomegalovirus UL97 protein: a quantitative analysis using recombinant vaccinia viruses

1 reference

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7 January 2021

10.1016/S0969-8051(99)00105-5

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24 September 2017

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