Production of human antibody repertoires in transgenic mice (Q40885910)

24 September 2017

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title

Production of human antibody repertoires in transgenic mice (English)

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24 September 2017

Brüggemann M

1

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PubMed ID

9265725

24 September 2017

Taussig MJ

series ordinal

2

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24 September 2017

1 August 1997

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Current Opinion in Biotechnology

24 September 2017

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24 September 2017

8

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24 September 2017

4

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24 September 2017

455-458

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Strategies for expressing human antibody repertoires in transgenic mice

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Mice perform a human repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Dominant expression of a 1.3 Mb human Ig kappa locus replacing mouse light chain production.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Human immunoglobulin transgenes undergo rearrangement, somatic mutation and class switching in mice that lack endogenous IgM.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

High-avidity human IgG kappa monoclonal antibodies from a novel strain of minilocus transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Assembly and extension of yeast artificial chromosomes to build up a large locus

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Production of fully human antibodies by transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

The diversity of antigen-specific monoclonal antibodies from transgenic mice bearing human immunoglobulin gene miniloci

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Antibodies generated from human immunoglobulin miniloci in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Chimaeric monoclonal antibodies encoded by the human VH26 gene from naïve transgenic mice display a wide range of antigen-binding specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Antibody expression from the core region of the human IgH locus reconstructed in transgenic mice using bacteriophage P1 clones

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Complete physical map of the human immunoglobulin heavy chain constant region gene complex

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

The human immunoglobulin VH repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

A repertoire of monoclonal antibodies with human heavy chains from transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Human antibody production in transgenic mice: expression from 100 kb of the human IgH locus

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

A transgenic mouse that expresses a diversity of human sequence heavy and light chain immunoglobulins

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Transgenic mice containing a human heavy chain immunoglobulin gene fragment cloned in a yeast artificial chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

Creation of mice expressing human antibody light chains by introduction of a yeast artificial chromosome containing the core region of the human immunoglobulin kappa locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980068-7

7 January 2021

10.1016/S0958-1669(97)80068-7

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

9265725