Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera (Q40886828)

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English	Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera	scientific article

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scholarly article

1 reference

Europe PubMed Central

24 September 2017

Engineering the human thyrotropin receptor ectodomain from a non-secreted form to a secreted, highly immunoreactive glycoprotein that neutralizes autoantibodies in Graves' patients' sera (English)

1 reference

Europe PubMed Central

24 September 2017

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1 reference

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author name string

Chazenbalk GD

1

1 reference

Europe PubMed Central

24 September 2017

Jaume JC

2

1 reference

Europe PubMed Central

24 September 2017

McLachlan SM

3

1 reference

Europe PubMed Central

24 September 2017

Rapoport B

4

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Europe PubMed Central

24 September 2017

language of work or name

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publication date

1 July 1997

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Europe PubMed Central

24 September 2017

number of pages

7

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Journal of Biological Chemistry

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Europe PubMed Central

24 September 2017

272

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Europe PubMed Central

24 September 2017

30

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Europe PubMed Central

24 September 2017

18959-18965

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Europe PubMed Central

24 September 2017

The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Autoantibodies to the thyrotropin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Cloning, sequencing and expression of human TSH receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Prokaryotic expression of the thyrotropin receptor and identification of an immunogenic region of the protein using synthetic peptides.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Two-subunit structure of the human thyrotropin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Characterization of the extracellular region of the human thyrotrophin receptor expressed as a recombinant protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Expression of a human thyrotrophin receptor fragment in Escherichia coli and its interaction with the hormone and autoantibodies from patients with Graves' disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

The thyrotrophin hormone receptor of Graves' disease: overexpression of the extracellular domain in insect cells using recombinant baculovirus, immunoaffinity purification and analysis of autoantibody binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Induction of TSH binding inhibitory immunoglobulins with the extracellular domain of human thyrotropin receptor produced using baculovirus expression system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Expression of the extracellular domain of the thyrotropin receptor in the baculovirus system using a promoter active earlier than the polyhedrin promoter. Implications for the expression of functional highly glycosylated proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

The use of the amplifiable high-expression vector pEE14 to study the interactions of autoantibodies with recombinant human thyrotrophin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Heterogeneous responses of recombinant human thyrotropin receptor to immunoglobulins from patients with Graves' disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Expression of recombinant human thyrotropin receptor in myeloma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Graves' IgG recognizes linear epitopes in the human thyrotropin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Immunoglobulins from Graves' disease patients interact with different sites on TSH receptor/LH-CG receptor chimeras than either TSH or immunoglobulins from idiopathic myxedema patients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

An insertion in the human thyrotropin receptor critical for high affinity hormone binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Use of the recombinant human thyrotropin receptor (TSH-R) expressed in mammalian cell lines to assay TSH-R autoantibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Evidence for negative cooperativity among human thyrotropin receptors overexpressed in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Critical relationship between autoantibody recognition and thyrotropin receptor maturation as reflected in the acquisition of complex carbohydrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Both the 5' and 3' noncoding regions of the thyrotropin receptor messenger ribonucleic acid influence the level of receptor protein expression in transfected mamalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Overexpression of an immunologically-intact, secreted form of human thyroid peroxidase in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Monoclonal antibodies to the human TSH receptor: epitope mapping and binding to the native receptor on the basolateral plasma membrane of thyroid follicular cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Thyrotropin receptor autoantibodies in serum are present at much lower levels than thyroid peroxidase autoantibodies: analysis by flow cytometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Assembly of asparagine-linked oligosaccharides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Proposal for a common oligosaccharide intermediate in the synthesis of membrane glycoproteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Variant forms of the pig lutropin/choriogonadotropin receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Molecular cloning and sequencing of an alternatively spliced form of the human thyrotropin receptor transcript

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Cloning and sequencing of a 1.3 KB variant of human thyrotropin receptor mRNA lacking the transmembrane domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Studies on the binding activity for the long-acting thyroid stimulator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Recombinant thyroid autoantigens: the keys to the pathogenesis of autoimmune thyroid disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Extracellular domain chimeras of the TSH and LH/CG receptors reveal the mid-region (amino acids 171-260) to play a vital role in high affinity TSH binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.30.18959

21 January 2018

Identifiers

10.1074/JBC.272.30.18959

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

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