The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways. (Q40887253)

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English	The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways.	scientific article

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5 November 2019

The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways (English)

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5 November 2019

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5 November 2019

Olivier Bernard

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5 November 2019

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Voss J

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5 November 2019

Posern G

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5 November 2019

Hannemann JR

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5 November 2019

Wiedemann LM

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5 November 2019

Poirel H

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5 November 2019

Adermann K

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Kardinal C

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5 November 2019

Feller SM

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1 March 2000

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5 November 2019

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5 November 2019

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5 November 2019

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5 November 2019

1684-1690

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5 November 2019

BCR-ABL and constitutively active erythropoietin receptor (cEpoR) activate distinct mechanisms for growth factor-independence and inhibition of apoptosis in Ba/F3 cell line.

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7 January 2021

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Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

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7 January 2021

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Tyrosine 207 in CRKL is the BCR/ABL phosphorylation site

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7 January 2021

based on heuristic

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bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

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7 January 2021

based on heuristic

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c-Abl kinase regulates the protein binding activity of c-Crk

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7 January 2021

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Physiological signals and oncogenesis mediated through Crk family adapter proteins

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7 January 2021

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Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

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Haemopoietic transformation by the TEL/ABL oncogene.

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7 January 2021

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Acute leukaemia in bcr/abl transgenic mice

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Structural organization of the bcr gene and its role in the Ph' translocation

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P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

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7 January 2021

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Protein tyrosine kinases and cancer

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A novel human gene closely related to the abl proto-oncogene

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The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases

1 reference

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Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

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7 January 2021

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Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells

1 reference

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A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

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ETV6/ABL fusion is rare in Ph-negative chronic myeloid disorders

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The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins

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The TEL gene products: nuclear phosphoproteins with DNA binding properties

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Activity of Rap1 is regulated by bombesin, cell adhesion, and cell density in NIH3T3 fibroblasts

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Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

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7 January 2021

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The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation

1 reference

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Signal transduction by wild-type and leukemogenic Abl proteins.

1 reference

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Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites

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p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene

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Chronic myeloid leukemia

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Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

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Cell cycle-dependent activation of Ras.

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