Interaction of Drosophila melanogaster prohormone convertase 2 and 7B2. Insect cell-specific processing and secretion (Q40889007)

24 September 2017

Interaction of Drosophila melanogaster prohormone convertase 2 and 7B2. Insect cell-specific processing and secretion (English)

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24 September 2017

Drosophila melanogaster

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Amontillado Dmel_CG6438

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GOA release 2020-03-11

author name string

J R Hwang

1

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24 September 2017

D E Siekhaus

2

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24 September 2017

R S Fuller

3

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24 September 2017

P H Taghert

4

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24 September 2017

I Lindberg

5

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24 September 2017

language of work or name

English

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publication date

1 June 2000

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Journal of Biological Chemistry

24 September 2017

8

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based on heuristic

inferred from page(s)

published in

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24 September 2017

275

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24 September 2017

23

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24 September 2017

17886-17893

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The proprotein convertases

24 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Eukaryotic protein processing: endoproteolysis of precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Proteolytic processing in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

A new type of synthetic peptide library for identifying ligand-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Identification of a Second Human Subtilisin-Like Protease Gene in thefes/fpsRegion of Chromosome 15

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Structure of the gene for the testis-specific proprotein convertase 4 and of its alternate messenger RNA isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

PC8 [corrected], a new member of the convertase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Role of the prohormone convertase PC2 in the processing of proglucagon to glucagon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

The role of prohormone convertases PC1 (PC3) and PC2 in the cell-specific processing of proglucagon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Isolation and NH2-terminal sequence of a novel porcine anterior pituitary polypeptide. Homology to proinsulin, secretin and Rous sarcoma virus transforming protein TVFV60.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

7B2 is a specific intracellular binding protein of the prohormone convertase PC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

The novel pituitary polypeptide 7B2 is a highly-conserved protein coexpressed with proopiomelanocortin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

A 36-residue peptide contains all of the information required for 7B2-mediated activation of prohormone convertase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Enzymatic characterization of immunopurified prohormone convertase 2: potent inhibition by a 7B2 peptide fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

The role of the 7B2 CT peptide in the inhibition of prohormone convertase 2 in endocrine cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Immunological identification and sequence characterization of a peptide derived from the processing of neuroendocrine protein 7B2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Mechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

The neuroimmunology of stress from invertebrates to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Peptidergic neurohormonal control systems in invertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Molluscan putative prohormone convertases: structural diversity in the central nervous system of Lymnaea stagnalis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Identification of a molluscan homologue of the neuroendocrine polypeptide 7B2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Isolation and in situ localization of a cDNA encoding a Kex2-like prohormone convertase in the nematode Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Cloning and functional analysis of C. elegans 7B2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Molecular cloning and cellular localization of a furin-like prohormone convertase from the atrial gland of Aplysia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Mutations within the propeptide, the primary cleavage site or the catalytic site, or deletion of C-terminal sequences, prevents secretion of proPC2 from transfected COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

An immunocytochemical study of the FMRFamide neuropeptide gene products in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Spatial and temporal expression identify dromyosuppressin as a brain-gut peptide in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Isolation and structure of the Drosophila corazonin gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Protein 7B2 is essential for the targeting and activation of PC2 into the regulated secretory pathway of rMTC 6-23 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Neuroendocrine protein 7B2 is essential for proteolytic conversion and activation of proprotein convertase 2 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Structural elements of PC2 required for interaction with its helper protein 7B2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

The NH2-terminal proregion of peptidylglycine alpha-amidating monooxygenase facilitates the secretion of soluble proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Role of PC2 in proenkephalin processing: antisense and overexpression studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Purification and enzymatic characterization of recombinant prohormone convertase 2: stabilization of activity by 21 kDa 7B2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Identification of the region within the neuroendocrine polypeptide 7B2 responsible for the inhibition of prohormone convertase PC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

Disruption of a behavioral sequence by targeted death of peptidergic neurons in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000032200

21 January 2018

Identifiers

DOI

10.1074/JBC.M000032200

1 reference

24 September 2017

1 reference