Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein (Q40893160)

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English	Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein	scientific article

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scholarly article

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Europe PubMed Central

24 September 2017

Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein (English)

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Europe PubMed Central

24 September 2017

Human T-lymphotropic virus 1

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author name string

E W Harhaj

1

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Europe PubMed Central

24 September 2017

L Good

2

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Europe PubMed Central

24 September 2017

G Xiao

3

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Europe PubMed Central

24 September 2017

M Uhlik

4

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Europe PubMed Central

24 September 2017

M E Cvijic

5

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Europe PubMed Central

24 September 2017

I Rivera-Walsh

6

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Europe PubMed Central

24 September 2017

S C Sun

7

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Europe PubMed Central

24 September 2017

language of work or name

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publication date

1 March 2000

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Europe PubMed Central

24 September 2017

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Europe PubMed Central

24 September 2017

19

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24 September 2017

1448-1456

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24 September 2017

11

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Europe PubMed Central

24 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203445

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The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene

1 reference

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21 January 2018

The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function

1 reference

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21 January 2018

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Autoregulation of I kappa B alpha activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

The regulation and roles of Rel/NF-kappa B transcription factors during lymphocyte activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

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21 January 2018

CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappaB/Rel heterodimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Cis-acting transcriptional regulatory sequences in the gibbon ape leukemia virus (GALV) long terminal repeat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Inactivation of IkappaBbeta by the tax protein of human T-cell leukemia virus type 1: a potential mechanism for constitutive induction of NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

21 January 2018

Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

7 January 2021

based on heuristic

inferred from DOI database lookup

Persistent activation of NF-kappa B/Rel by human T-cell leukemia virus type 1 tax involves degradation of I kappa B beta.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

7 January 2021

based on heuristic

inferred from DOI database lookup

IkappaB kinases serve as a target of CD28 signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

7 January 2021

based on heuristic

inferred from DOI database lookup

The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

7 January 2021

based on heuristic

inferred from DOI database lookup

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

7 January 2021

based on heuristic

inferred from DOI database lookup

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203445

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/SJ.ONC.1203445

1 reference

Europe PubMed Central

24 September 2017

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1 reference

Europe PubMed Central

24 September 2017

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