Homeodomain protein IDX-1: a master regulator of pancreas development and insulin gene expression (Q40894548)

24 September 2017

Homeodomain protein IDX-1: a master regulator of pancreas development and insulin gene expression (English)

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24 September 2017

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3

Habener JF

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24 September 2017

Stoffers DA

1

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PubMed ID

18406800

24 September 2017

Thomas MK

series ordinal

2

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PubMed ID

18406800

24 September 2017

language of work or name

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1 May 1997

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Trends in Endocrinology and Metabolism

24 September 2017

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24 September 2017

8

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24 September 2017

4

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24 September 2017

145-151

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Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons.

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Glucokinase mutations, insulin secretion, and diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Nutrient regulation of insulin gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Autonomous endodermal determination in Xenopus: regulation of expression of the pancreatic gene XlHbox 8.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

The insulin gene promoter. A simplified nomenclature.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

The insulin gene contains multiple transcriptional elements that respond to glucose

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Transcriptional activation by tetracyclines in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Isolation, characterization, and chromosomal mapping of the human insulin promoter factor 1 (IPF-1) gene

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Glucose modulates the binding activity of the beta-cell transcription factor IUF1 in a phosphorylation-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Transplanted beta cell response to increased metabolic demand. Changes in beta cell replication and mass

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Multiple functions for Pax6 in mouse eye and nasal development.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Pancreatic islet expression of the homeobox factor STF-1 relies on an E-box motif that binds USF.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Regulation of insulin gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Localization of Human Homeodomain Transcription Factor Insulin Promoter Factor I (IPF1) to Chromosome Band 13q12.1

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Pancreatic beta-cell growth and diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Cell lineage analysis of pancreatic islet development: glucagon and insulin cells arise from catecholaminergic precursors present in the pancreatic duct

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Evidence for a new family of evolutionarily conserved homeobox genes

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Early Pancreas Organogenesis: Morphogenesis, Tissue Interactions, and Mass Effects

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

Ontogenetic appearance of immunoreactive endocrine cells in rat pancreatic islets.

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2897%2900008-8

7 January 2021

10.1016/S1043-2760(97)00008-8

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

18406800