DNA methylation, heterochromatin and epigenetic carcinogens (Q40899609)

24 September 2017

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title

DNA methylation, heterochromatin and epigenetic carcinogens (English)

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24 September 2017

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Klein CB

1

1 reference

PubMed ID

9113117

24 September 2017

Costa M

series ordinal

2

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PubMed ID

9113117

24 September 2017

language of work or name

English

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publication date

1 April 1997

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24 September 2017

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24 September 2017

386

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24 September 2017

2

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24 September 2017

163-180

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Epigenetic regulation of the maize Spm transposon

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

HGPRT- mutants of V79 cells that revert specifically by base pair substitution and frameshift mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Modeling and measurement of the spontaneous mutation rate in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Chemicals for evaluating the sensitivity and specificity of reduced/transgenic rodent cancer bioassay protocols.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

International Commission for Protection Against Environmental Mutagens and Carcinogens. Two million rodent carcinogens? The role of SAR and QSAR in their detection

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Genetic toxicity in relation to receptor-mediated carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Diethylstilbestrol induces neoplastic transformation without measurable gene mutation at two loci.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Mechanisms for species differences in receptor-mediated carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Nonrandom karyotypic changes in immortal and tumorigenic Syrian hamster cells induced by diethylstilbestrol

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Induction of chromosome aberrations in Syrian hamster renal cortical cells by various estrogens

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Model for the epigenetic mechanism of action of nongenotoxic carcinogens

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Nongenotoxic carcinogens: development of detection methods based on mechanisms: a European project

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

DNA methylation and development

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Some milestones in the history of X-chromosome inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

CpG islands and genes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

The essentials of DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Loss of methylation activates Xist in somatic but not in embryonic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Sequence specificity of methylation in higher plant DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

CpNpG methylation in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Changes of the methylation pattern of the c-myc gene during in vitro aging of IMR90 human embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Mutagenic and epigenetic effects of DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

The CpG dinucleotide and human genetic disease

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

The pattern of spontaneous germ-line mutation: relative rates of mutation at or near CpG dinucleotides in the factor IX gene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

DNA methylation and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

A mutant HpaII methyltransferase functions as a mutator enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

High frequency mutagenesis by a DNA methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Increased cytosine DNA-methyltransferase activity during colon cancer progression

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Genomic imprinting: lessons from mouse transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Multiple mutations in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Mutations and epimutations in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

A possible role in chemical carcinogenesis for epigenetic, heritable changes in gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Allele-specific methylation of the human c-Ha-ras-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

William L. McGuire Memorial Symposium. The role and prognostic significance of p53 gene alterations in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Comparison of the age- and tumor-associated changes in the c-myc gene methylation in mouse liver

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Alterations of c-fos gene methylation in the processes of aging and tumorigenesis in human liver

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Clues to the pathogenesis of familial colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Suppression of intestinal neoplasia by DNA hypomethylation.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Gene number, noise reduction and biological complexity

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

5-Methylcytosine is not detectable in Saccharomyces cerevisiae DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

The absence of detectable methylated bases in Drosophila melanogaster DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Position effect variegation in Drosophila: towards a genetics of chromatin assembly

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Histone acetylation and gene induction in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

X-chromosome inactivation and cell memory

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Position-effect variegation and the new biology of heterochromatin

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Epigenetic repeat-induced gene silencing (RIGS) in Arabidopsis.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Determination of trace amounts of 5-methylcytosine in DNA by reverse-phase high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

A group of scs elements function as domain boundaries in an enhancer-blocking assay

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

A sequence motif found in aDrosophilaheterochromatin protein is conserved in animals and plants

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Control of chromosome inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Position effect variegation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Methylation analysis of CGG sites in the CpG island of the human FMR1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Binding of histone H1 to DNA is indifferent to methylation at CpG sequences.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

The repressor MDBP-2 is a member of the histone H1 family that binds preferentially in vitro and in vivo to methylated nonspecific DNA sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Methylated DNA-binding protein is present in various mammalian cell types

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Interaction and conformational changes of chromatin with divalent ions.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Transcriptional regulation of multigene loci: multilevel control

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Locus control region function and heterochromatin-induced position effect variegation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Epigenetic gene inactivation induced by a cis-acting methylation center.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Chromatin structure and developmental expression of the human alpha-globin cluster

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Telomere-proximal DNA in Saccharomyces cerevisiae is refractory to methyltransferase activity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

SUM1-1, a dominant suppressor of SIR mutations in Saccharomyces cerevisiae, increases transcriptional silencing at telomeres and HM mating-type loci and decreases chromosome stability

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Hypermethylation of telomere-like foldbacks at codon 12 of the human c-Ha-ras gene and the trinucleotide repeat of the FMR-1 gene of fragile X.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

DNA methylation in eukaryotic chromosome stability

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Trinucleotide repeats that expand in human disease form hairpin structures in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Interchromosomal Transfer of Epigenetic States in Ascobolus: Transfer of DNA Methylation Is Mechanistically Related to Homologous Recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Molecular mechanisms of nickel carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Mutagenic responses of nickel oxides and nickel sulfides in Chinese hamster V79 cell lines at the xanthine-guanine phosphoribosyl transferase locus

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

The role of oxidative processes in metal carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Nickel induces increased oxidants in intact cultured mammalian cells as detected by dichlorofluorescein fluorescence

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Crystalline Ni3S2 specifically enhances the formation of oxidants in the nuclei of CHO cells as detected by dichlorofluorescein

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Possible role of oxidative damage in metal-induced carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Heterochromatic proteins specifically enhance nickel-induced 8-oxo-dG formation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Mechanisms involved in the immortalization of mammalian cells by ionizing radiation and chemical carcinogens.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Transgenic Chinese hamster V79 cell lines which exhibit variable levels of gpt mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Transgenic gpt+ V79 cell lines differ in their mutagenic response to clastogens

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Mutagenicity of soluble and insoluble nickel compounds at the gpt locus in G12 Chinese hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

The chromosomes of a V79 Chinese hamster line and a mutant subline lacking HPRT activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Modulation of transfected gene expression mediated by changes in chromatin structure

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Parental legacy determines methylation and expression of an autosomal transgene: a molecular mechanism for parental imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Expression of a foreign gene in a line of transgenic mice is modulated by a chromosomal position effect

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Altering genotype and phenotype by DNA-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Phenotypic switching in cells transformed with the herpes simplex virus thymidine kinase gene

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

De novo methylation as major event in the inactivation of transfected herpesvirus thymidine kinase genes in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

DNA methylation and chromatin structure: a view from below

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Genome wide spontaneous mutation in human cells determined by the spectrum of mutations in hprt cDNA genes

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Induction of thymidine kinase in enzyme-deficient chinese hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

At least two distinct epigenetic mechanisms are correlated with high-frequency "switching" for APRT phenotypic expression in mouse embryonal carcinoma stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Alterations in c-abl gene methylation in cells transformed by phagocyte-generated oxidants.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Free radical adducts induce alterations in DNA cytosine methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

DNA adduct 8-hydroxyl-2'-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Inactivation of a transfected gene in human fibroblasts can occur by deletion, amplification, phenotypic switching, or methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Mutagenic treatments result in inactivation of expression of a transfected bacterial gene integrated into a human cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

Drug-induced DNA hypermethylation: a potential mediator of acquired drug resistance during cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

DNA demethylation in vitro: involvement of RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5742%2896%2900052-X

7 January 2021

10.1016/S1383-5742(96)00052-X

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

9113117