The bacterial cytolethal distending toxin (CDT) triggers a G2 cell cycle checkpoint in mammalian cells without preliminary induction of DNA strand breaks. (Q40912299)

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English	The bacterial cytolethal distending toxin (CDT) triggers a G2 cell cycle checkpoint in mammalian cells without preliminary induction of DNA strand breaks.	scientific article

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2 November 2019

The bacterial cytolethal distending toxin (CDT) triggers a G2 cell cycle checkpoint in mammalian cells without preliminary induction of DNA strand breaks (English)

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2 November 2019

Bernard Ducommun

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2 November 2019

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Sert V

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2 November 2019

Cans C

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2 November 2019

Tasca C

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2 November 2019

Bret-Bennis L

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2 November 2019

Oswald E

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2 November 2019

De Rycke J

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2 November 2019

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1 November 1999

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2 November 2019

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2 November 2019

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2 November 2019

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2 November 2019

6296-6304

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2 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203007

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Alternative splicing of the human CDC25B tyrosine phosphatase. Possible implications for growth control?

1 reference

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21 January 2018

Replication checkpoint enforced by kinases Cds1 and Chk1.

1 reference

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21 January 2018

The cytolethal distending toxin from the chancroid bacterium Haemophilus ducreyi induces cell-cycle arrest in the G2 phase

1 reference

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21 January 2018

A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells/.

1 reference

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21 January 2018

Caffeine overcomes a restriction point associated with DNA replication, but does not accelerate mitosis

1 reference

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21 January 2018

Cell cycle checkpoints: preventing an identity crisis

1 reference

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HHR23A, the human homologue of the yeast repair protein RAD23, interacts specifically with Vpr protein and prevents cell cycle arrest but not the transcriptional effects of Vpr.

1 reference

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21 January 2018

Inhibition of DNA topoisomerase II by ICRF-193 induces polyploidization by uncoupling chromosome dynamics from other cell cycle events

1 reference

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21 January 2018

The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts

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21 January 2018

Mechanism by which caffeine potentiates lethality of nitrogen mustard

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21 January 2018

DNA topoisomerase poisons as antitumor drugs

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21 January 2018

Hypersensitivity of Ku-deficient cells toward the DNA topoisomerase II inhibitor ICRF-193 suggests a novel role for Ku antigen during the G2 and M phases of the cell cycle

1 reference

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21 January 2018

When checkpoints fail

1 reference

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21 January 2018

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

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21 January 2018

A new cytolethal distending toxin (CDT) from Escherichia coli producing CNF2 blocks HeLa cell division in G2/M phase

1 reference

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21 January 2018

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

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21 January 2018

A simple technique for quantitation of low levels of DNA damage in individual cells

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Cell cycle control of DNA replication.

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Discrimination between genotoxicity and cytotoxicity in the induction of DNA double-strand breaks in cells treated with etoposide, melphalan, cisplatin, potassium cyanide, Triton X-100, and gamma-irradiation

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21 January 2018

Escherichia coli cytolethal distending toxin blocks the HeLa cell cycle at the G2/M transition by preventing cdc2 protein kinase dephosphorylation and activation

1 reference

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7 January 2021

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DNA signals for G2 checkpoint response in diploid human fibroblasts

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A critical appraisal of synchronization methods applied to achieve maximal enrichment of HeLa cells in specific cell cycle phases

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Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship

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Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay

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Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard

1 reference

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Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells

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7 January 2021

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Campylobacter jejuni cytolethal distending toxin causes a G2-phase cell cycle block.

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Two S-phase checkpoint systems, one involving the function of both BIME and Tyr15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis.

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10.1038/SJ.ONC.1203007

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2 November 2019

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24 November 2022

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2 November 2019

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