Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1. (Q40920177)

24 September 2017

Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1. (English)

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24 September 2017

P Schär

4

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author name string

M Räschle

1

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24 September 2017

G Marra

2

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24 September 2017

M Nyström-Lahti

3

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24 September 2017

J Jiricny

5

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24 September 2017

language of work or name

English

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publication date

1 November 1999

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Journal of Biological Chemistry

24 September 2017

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24 September 2017

274

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24 September 2017

32368-32375

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24 September 2017

45

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Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

24 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

21 January 2018

1 reference

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Microsatellite instability in cancer of the proximal colon

21 January 2018

1 reference

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Clues to the pathogenesis of familial colorectal cancer

21 January 2018

1 reference

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Genetic mapping of a locus predisposing to human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Mutation of a mutL homolog in hereditary colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

DNA mismatch repair gene mutations in 55 kindreds with verified or putative hereditary non-polyposis colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Mismatch repair deficiency associated with overexpression of the MSH3 gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Hypermutability and mismatch repair deficiency in RER+ tumor cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Functional domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA mismatch repair proteins and their relevance to human hereditary nonpolyposis colorectal cancer-associated mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Eukaryotic DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

A human 200-kDa protein binds selectively to DNA fragments containing G.T mismatches

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Mismatch repair defects and O6-methylguanine-DNA methyltransferase expression in acquired resistance to methylating agents in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

A hPMS2 mutant cell line is defective in strand-specific mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Different mutator phenotypes in Mlh1- versus Pms2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Characterization of distinct human endometrial carcinoma cell lines deficient in mismatch repair that originated from a single tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32368

21 January 2018

Identifiers

DOI

10.1074/JBC.274.45.32368

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24 September 2017

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