Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response (Q40921231)

24 September 2017

Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response (English)

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24 September 2017

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Paterson M

1

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24 September 2017

Laxton CD

2

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24 September 2017

Thomas HC

3

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24 September 2017

Ackrill AM

4

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24 September 2017

Foster GR

5

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24 September 2017

language of work or name

English

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publication date

1 November 1999

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24 September 2017

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24 September 2017

117

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24 September 2017

5

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24 September 2017

1187-1197

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Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis

24 September 2017

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https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Genetic organization and diversity of the hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Long-term follow-up of patients with chronic hepatitis C treated with α-interferon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Management of hepatitis C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

How cells respond to interferons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Viral inhibition of the interferon system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Clinical relevance of hepatitis C virus quasispecies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Mutations in the nonstructural 5A gene of European hepatitis C virus isolates and response to interferon alfa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Mutations in the nonstructural 5A region of hepatitis C virus and response of chronic hepatitis C to interferon alfa.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence do not predict the response to recombinant interferon-alfa therapy in French patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Sequence analysis of the NS5A protein of European hepatitis C virus 1b isolates and relation to interferon sensitivity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

The prognostic relevance of the nonstructural 5A gene interferon sensitivity determining region is different in infections with genotype 1b and 3a isolates of hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Characterization of the effects of hepatitis C virus nonstructural 5A protein expression in human cell lines and on interferon-sensitive virus replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

The NS5A protein of hepatitis C virus partially inhibits the antiviral activity of interferon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Different relative activities of human cell-derived interferon-alpha subtypes: IFN-alpha 8 has very high antiviral potency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

Differential response of the human 6-16 and 9-27 genes to alpha and gamma interferons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970405-1

10.1016/S0016-5085(99)70405-1

7 January 2021

Identifiers

DOI

1 reference

release_q223ytyks5hvnp73bpmfyhy6ka

24 September 2017

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Fatcat

https://api.fatcat.wiki/v0/release/q223ytyks5hvnp73bpmfyhy6ka

mapped directly with Wikidata item

24 November 2022

based on heuristic

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