Molecular analysis of the physiological and pathophysiological role of alpha 4-integrins (Q40922417)

24 September 2017

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title

Molecular analysis of the physiological and pathophysiological role of alpha 4-integrins (English)

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24 September 2017

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G Kilger

1

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24 September 2017

B Holzmann

series ordinal

2

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24 September 2017

publication date

1 July 1995

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Journal of Molecular Medicine

24 September 2017

published in

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24 September 2017

volume

73

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24 September 2017

issue

7

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24 September 2017

page(s)

347-354

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Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.

24 September 2017

cites work

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12 December 2020

Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells.

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12 December 2020

An inducible endothelial cell surface glycoprotein mediates melanoma adhesion

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12 December 2020

Upregulated expression and function of VLA-4 fibronectin receptors on human activated T cells in rheumatoid arthritis

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12 December 2020

Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD protein

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12 December 2020

Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma

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12 December 2020

Lymphocyte adhesion through very late antigen 4: evidence for a novel binding site in the alternatively spliced domain of vascular cell adhesion molecule 1 and an additional alpha 4 integrin counter-receptor on stimulated endothelium

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12 December 2020

The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine.

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12 December 2020

Physiology of Thrombospondin

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12 December 2020

Alpha E beta 7 and alpha 4 beta 7 integrins associated with intraepithelial and mucosal homing, are expressed on macrophages

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12 December 2020

VLA-4 integrin can mediate CD11/CD18-independent transendothelial migration of human monocytes

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12 December 2020

Very late activation antigen 4-vascular cell adhesion molecule 1 interaction is involved in the formation of erythroblastic islands

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12 December 2020

A two-step adhesion cascade for T cell/endothelial cell interactions under flow conditions

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12 December 2020

Endothelial-leukocyte adhesion molecules

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12 December 2020

Anchorage dependence, integrins, and apoptosis

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12 December 2020

Alpha 4 beta 1 and alpha 5 beta 1 are differentially expressed during myelopoiesis and mediate the adherence of human CD34+ cells to fibronectin in an activation-dependent way

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12 December 2020

Lymphocyte interactions with endothelial cells

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12 December 2020

VLA-4 mediates CD3-dependent CD4+ T cell activation via the CS1 alternatively spliced domain of fibronectin

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12 December 2020

Activation of the alpha 4 beta 1 integrin through the beta 1 subunit induces recognition of the RGDS sequence in fibronectin

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12 December 2020

Two integrin-binding peptides abrogate T cell-mediated immune responses in vivo

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12 December 2020

Dual inhibition of VLA-4 and LFA-1 maximally inhibits cutaneous delayed-type hypersensitivity-induced inflammation.

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12 December 2020

MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1

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12 December 2020

Integrin-mediated cell adhesion: the extracellular face

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12 December 2020

Alpha 4-integrins mediate antigen-induced late bronchial responses and prolonged airway hyperresponsiveness in sheep

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12 December 2020

Regulated expression and binding of three VLA (beta 1) integrin receptors on T cells

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12 December 2020

Interchangeable alpha chain cytoplasmic domains play a positive role in control of cell adhesion mediated by VLA-4, a beta 1 integrin

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12 December 2020

Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction

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12 December 2020

Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin

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12 December 2020

Very late antigen 4-dependent adhesion and costimulation of resting human T cells by the bacterial beta 1 integrin ligand invasin

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12 December 2020

Expression of a protective intestinal immune response can be inhibited at three distinct sites by treatment with anti-alpha 4 integrin

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12 December 2020

Expression of homing and adhesion molecules in infiltrated islets of Langerhans and salivary glands of nonobese diabetic mice

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12 December 2020

Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha

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12 December 2020

Differential regulation of alpha 4 integrin-dependent binding to domains 1 and 4 of vascular cell adhesion molecule-1

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12 December 2020

A predominant role of integrin alpha 4 in the spontaneous development of autoimmune diabetes in nonobese diabetic mice

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12 December 2020

The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.

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12 December 2020

Differential expression in rheumatoid synovium and synovial fluid of alpha 4 beta 7 integrin. A novel receptor for fibronectin and vascular cell adhesion molecule-1

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12 December 2020

Inhibition of insulitis and prevention of diabetes in nonobese diabetic mice by blocking L-selectin and very late antigen 4 adhesion receptors

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12 December 2020

Mutation of putative divalent cation sites in the alpha 4 subunit of the integrin VLA-4: distinct effects on adhesion to CS1/fibronectin, VCAM-1, and invasin

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12 December 2020

Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody. A likely role for VLA-4 in vivo

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12 December 2020

Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis

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12 December 2020

Identification of a key integrin-binding sequence in VCAM-1 homologous to the LDV active site in fibronectin

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12 December 2020

Functional and structural analysis of VLA-4 integrin alpha 4 subunit cleavage

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12 December 2020

Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes

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12 December 2020

Vascular cell adhesion molecule 1 induces T-cell antigen receptor-dependent activation of CD4+T lymphocytes

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12 December 2020

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

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12 December 2020

The contributions of integrins to leukocyte infiltration in inflamed tissues

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12 December 2020

Activated endothelium binds lymphocytes through a novel binding site in the alternately spliced domain of vascular cell adhesion molecule-1

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12 December 2020

Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation

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12 December 2020

Alpha 4/180, a novel form of the integrin alpha 4 subunit.

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12 December 2020

Affinity chromatographic isolation of the melanoma adhesion receptor for the IIICS region of fibronectin and its identification as the integrin alpha 4 beta 1.

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12 December 2020

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion

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12 December 2020

A tissue-specific endothelial cell molecule involved in lymphocyte homing

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12 December 2020

Distinct binding specificities of integrins alpha 4 beta 7 (LPAM-1), alpha 4 beta 1 (VLA-4), and alpha IEL beta 7

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12 December 2020

Expression of integrins and examination of their adhesive function in normal and leukemic hematopoietic cells

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12 December 2020

Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis

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12 December 2020

Prevention of mercuric chloride-induced nephritis in the brown Norway rat by treatment with antibodies against the alpha 4 integrin

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12 December 2020

CD9 antigen is an accessory subunit of the VLA integrin complexes.

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12 December 2020

Lymphocyte surface antigen L25 is a member of the integrin receptor superfamily.

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12 December 2020

The CS5 peptide is a second site in the IIICS region of fibronectin recognized by the integrin alpha 4 beta 1. Inhibition of alpha 4 beta 1 function by RGD peptide homologues

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12 December 2020

Monoclonal antibodies to the integrin alpha-4 subunit inhibit the murine contact hypersensitivity response.

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12 December 2020

Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody

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12 December 2020

Arrangement of domains, and amino acid residues required for binding of vascular cell adhesion molecule-1 to its counter-receptor VLA-4 (alpha 4 beta 1).

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12 December 2020

Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1.

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12 December 2020

Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B cell precursors to cultured bone marrow adherent cells

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12 December 2020

Immunosuppression to cardiac allografts and soluble antigens by anti-vascular cellular adhesion molecule-1 and anti-very late antigen-4 monoclonal antibodies

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12 December 2020

VLA-4 integrin mediates lymphocyte migration on the inducible endothelial cell ligand VCAM-1 and the extracellular matrix ligand fibronectin

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12 December 2020

Signals and signs for lymphocyte responses

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12 December 2020

Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin

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12 December 2020

T lymphocyte migration to arthritic joints and dermal inflammation in the rat: differing migration patterns and the involvement of VLA-4

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12 December 2020

Expanding roles for alpha 4 integrin and its ligands in development

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12 December 2020

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site.

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12 December 2020

Monocytes use either CD11/CD18 or VLA-4 to migrate across human endothelium in vitro

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12 December 2020

The pathogenesis of adoptive murine autoimmune diabetes requires an interaction between alpha 4-integrins and vascular cell adhesion molecule-1.

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12 December 2020

Activated T-cell adhesion to thrombospondin is mediated by the alpha 4 beta 1 (VLA-4) and alpha 5 beta 1 (VLA-5) integrins.

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12 December 2020

Antigen-independent processes in antigen-specific immunity. A role for alpha 4 integrin

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12 December 2020

Regulation of the avidity of integrin alpha 4 beta 7 by the beta 7 cytoplasmic domain.

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12 December 2020

The heat-stable antigen can alter very late antigen 4-mediated adhesion

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12 December 2020

Physiological and molecular mechanisms of lymphocyte homing

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12 December 2020

VLA-3: a novel polypeptide association within the VLA molecular complex: cell distribution and biochemical characterization

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12 December 2020

CD9-regulated adhesion. Anti-CD9 monoclonal antibody induce pre-B cell adhesion to bone marrow fibroblasts through de novo recognition of fibronectin

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12 December 2020

Stimulation of protein tyrosine phosphorylation in human B cells after ligation of the beta 1 integrin VLA-4

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12 December 2020

Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

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12 December 2020

Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue

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12 December 2020

Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo

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12 December 2020

Structural requirements for adhesion of soluble recombinant murine vascular cell adhesion molecule-1 to alpha 4 beta 1.

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12 December 2020

Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7

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12 December 2020

Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes

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12 December 2020

Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4

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12 December 2020

Selective expression of integrin alpha 4 beta 7 on a subset of human CD4+ memory T cells with Hallmarks of gut-trophism.

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12 December 2020

Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1

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12 December 2020

Protection against adoptive transfer of autoimmune diabetes mediated through very late antigen-4 integrin

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12 December 2020

Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing

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12 December 2020

Antibody to very late activation antigen 4 prevents antigen-induced bronchial hyperreactivity and cellular infiltration in the guinea pig airways

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12 December 2020

Control of lymphocyte homing

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12 December 2020

Adhesion of human B cells to germinal centers in vitro involves VLA-4 and INCAM-110

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12 December 2020

Alpha 4 beta 7 integrin mediates B cell binding to fibronectin and vascular cell adhesion molecule-1. Expression and function of alpha 4 integrins on human B lymphocytes

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12 December 2020

Structure of the integrin VLA-4 and its cell-cell and cell-matrix adhesion functions

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12 December 2020

Expression of the integrin alpha 4 beta 1 on melanoma cells can inhibit the invasive stage of metastasis formation.

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12 December 2020

Adhesion of human B cells to follicular dendritic cells involves both the lymphocyte function-associated antigen 1/intercellular adhesion molecule 1 and very late antigen 4/vascular cell adhesion molecule 1 pathways

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12 December 2020

Integrins: versatility, modulation, and signaling in cell adhesion

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12 December 2020

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma

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12 December 2020

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

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12 December 2020

L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo

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12 December 2020

CD18-independent neutrophil and mononuclear leukocyte emigration into the peritoneum of rabbits

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12 December 2020

The role of the leukocyte adhesion molecules VLA-4, LFA-1, and Mac-1 in allergic airway responses in the rat.

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12 December 2020

The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent

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12 December 2020

Multiple activation states of VLA-4. Mechanistic differences between adhesion to CS1/fibronectin and to vascular cell adhesion molecule-1

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12 December 2020

Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering

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12 December 2020

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

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12 December 2020

alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow

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12 December 2020

Identification of a novel recognition sequence for the integrin alpha 4 beta 1 in the COOH-terminal heparin-binding domain of fibronectin

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12 December 2020

A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture

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12 December 2020

Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.

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12 December 2020

The alpha 4 beta 1/VCAM-1 adhesion pathway in physiology and disease

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12 December 2020

Activation Dependent and Independent VLA-4 Binding Sites on Vascular Cell Adhesion Molecule-1

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12 December 2020

Distinct cellular functions mediated by different VLA integrin alpha subunit cytoplasmic domains

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12 December 2020

Monocyte migration to arthritis in the rat utilizes both CD11/CD18 and very late activation antigen 4 integrin mechanisms

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12 December 2020

Vascular addressins are induced on islet vessels during insulitis in nonobese diabetic mice and are involved in lymphoid cell binding to islet endothelium

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12 December 2020

Leukocyte-endothelial adhesion molecules

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12 December 2020

Signaling by vascular cell adhesion molecule-1 (VCAM-1) through VLA-4 promotes CD3-dependent T cell proliferation

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12 December 2020

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

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12 December 2020

Coordinate expression of β1 and β2 integrin “activation” epitopes during T cell responses in secondary lymphoid tissue

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12 December 2020

Minimum alpha chain cytoplasmic tail sequence needed to support integrin-mediated adhesion.

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12 December 2020

The pathophysiologic role of alpha 4 integrins in vivo

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12 December 2020

Identifiers

DOI

10.1007/BF00192886

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release_n7qa25iihre5jiuigtkqj2bgfi

24 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/n7qa25iihre5jiuigtkqj2bgfi

24 November 2022

mapped directly with Wikidata item

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