Clinical importance of hepatic cytochrome P450 in drug metabolism (Q40923015)

24 September 2017

1 reference

title

Clinical importance of hepatic cytochrome P450 in drug metabolism (English)

1 reference

24 September 2017

Spatzenegger M

1

1 reference

PubMed ID

8521748

24 September 2017

Jaeger W

series ordinal

2

1 reference

PubMed ID

8521748

24 September 2017

language of work or name

English

0 references

publication date

1 January 1995

1 reference

24 September 2017

Drug Metabolism Reviews

1 reference

24 September 2017

27

1 reference

24 September 2017

3

1 reference

24 September 2017

397-417

1 reference

Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation

24 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Role of cytochromes P450 in drug metabolism and hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Role of human hepatic cytochromes P450 in drug metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Inducing effect of oxfendazole on cytochrome P450IA2 in rabbit liver. Consequences on cytochrome P450 dependent monooxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

In vitro and in vivo evidence for the formation of methyl radical from procarbazine: a spin-trapping study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Catalysis of the oxidation of steroid and stilbene estrogens to estrogen quinone metabolites by the beta-naphthoflavone-inducible cytochrome P450 IA family.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Monoclonal antibody-directed characterization of rat hepatic P450 catalyzing the omega-1 and omega-2 hydroxylation of prostaglandins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Species differences in metabolism and pharmacokinetics: are we close to an understanding?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Selective 3-hydroxylation deficiency of lidocaine and its metabolite in Dark Agouti rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Differential foetal development of the O- and N-demethylation of codeine and dextromethorphan in man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Oxidation of reduced haloperidol to haloperidol: involvement of human P450IID6 (sparteine/debrisoquine monooxygenase).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Catalytic selectivity of human cytochrome P450 enzymes: relevance to drug metabolism and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Maprotiline metabolism appears to co-segregate with the genetically-determined CYP2D6 polymorphic hydroxylation of debrisoquine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Metabolism of minaprine in human and animal hepatocytes and liver microsomes—prediction of metabolismin vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Stereoselective inhibition of nortriptyline hydroxylation in man by quinidine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

The pharmacokinetics of ondansetron after intravenous injection in healthy volunteers phenotyped as poor or extensive metabolisers of debrisoquine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Thebaine O-demethylation to oripavine: genetic differences between two rat strains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Characterization of ethanol-inducible human liver N-nitrosodimethylamine demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Identification of an inducible form of cytochrome P-450 in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Participation of P450 3A enzymes in rat hepatic microsomal retinoic acid 4-hydroxylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Species differences in ciprofibrate induction of hepatic cytochrome p450 4A1 and peroxisome proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Evaluation of loratadine as an inducer of liver microsomal cytochrome P450 in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Inhibitory potency of quinolone antibacterial agents against cytochrome P450IA2 activity in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

The dopamine transporter and cytochrome P45OIID1 (debrisoquine 4-hydroxylase) in brain: resolution and identification of two distinct [3H]GBR-12935 binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Distinct induction profiles of three phenobarbital-responsive mouse liver cytochrome P450 isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

Relation between chloroguanide bioactivation to cycloguanil and the genetically determined metabolism of mephenytoin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998329

10.3109/03602539508998329

21 January 2018

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

8521748