Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt. (Q40923070)

24 September 2017

Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt. (English)

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24 September 2017

4

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24 September 2017

A Craxton

1

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24 September 2017

A Jiang

series ordinal

2

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24 September 2017

T Kurosaki

series ordinal

3

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24 September 2017

language of work or name

English

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publication date

1 October 1999

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Journal of Biological Chemistry

24 September 2017

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24 September 2017

274

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24 September 2017

30644-30650

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24 September 2017

43

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Protein tyrosine kinases in the initiation of antigen receptor signaling

24 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Molecular mechanisms in B cell antigen receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

The complexity of signaling pathways activated by the BCR.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Positive and negative roles of the tyrosine kinase Lyn in B cell function

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Protein kinase C mu (PKC mu) associates with the B cell antigen receptor complex and regulates lymphocyte signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Syk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mitogen-activated protein kinase-independent pathway in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Different protein tyrosine kinases are required for B cell antigen receptor-mediated activation of extracellular signal-regulated kinase, c-Jun NH2-terminal kinase 1, and p38 mitogen-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

The inositol phosphatase SHIP inhibits Akt/PKB activation in B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

CREB is a regulatory target for the protein kinase Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Cross-linking of B cell antigen receptor-related structure of pre-B cell lines induces tyrosine phosphorylation of p85 and p110 subunits and activation of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.43.30644

21 January 2018

Identifiers

DOI

10.1074/JBC.274.43.30644

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24 September 2017

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