Ca2+-dependent activity of human DNase I and its hyperactive variants (Q40927903)

24 September 2017

Ca2+-dependent activity of human DNase I and its hyperactive variants (English)

1 reference

24 September 2017

Pan CQ

1

1 reference

PMC publication ID

2144401

24 September 2017

Lazarus RA

series ordinal

2

1 reference

24 September 2017

1 September 1999

1 reference

24 September 2017

1 reference

24 September 2017

8

1 reference

24 September 2017

9

1 reference

24 September 2017

1780-1788

1 reference

Site-directed mutagenesis of phosphate-contacting amino acids of bovine pancreatic deoxyribonuclease I.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Mutational analysis of human DNase I at the DNA binding interface: implications for DNA recognition, catalysis, and metal ion dependence

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Site-directed mutagenesis of the catalytic residues of bovine pancreatic deoxyribonuclease I.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Engineering actin-resistant human DNase I for treatment of cystic fibrosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

DNA recognition by DNase I.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Crystallographic refinement and structure of DNase I at 2 A resolution

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Atomic structure of the actin:DNase I complex

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

DNase I-induced DNA conformation. 2 A structure of a DNase I-octamer complex

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

X-ray structure of the DNase I-d(GGTATACC)2 complex at 2.3 A resolution

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

The essential role of Ca2+ in the activity of bovine pancreatic deoxyribonuclease

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Management of pulmonary disease in patients with cystic fibrosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Crystalline desoxyribonuclease; isolation and general properties; spectrophotometric method for the measurement of desoxyribonuclease activity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Expression and characterization of a DNase I-Fc fusion enzyme

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Improved potency of hyperactive and actin-resistant human DNase I variants for treatment of cystic fibrosis and systemic lupus erythematosus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Engineering hyperactive variants of human deoxyribonuclease I by altering its functional mechanism

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

The effect of divalent cations on the mode of action of DNase I. The initial reaction products produced from covalently closed circular DNA

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Hyperactivity of human DNase I variants. Dependence on the number of positively charged residues and concentration, length, and environment of DNA.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

X-ray structures of two single-residue mutants of DNase I: H134Q and Y76A.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2144401

Deoxyribonucleic acid nucleases. II. The effects of metals on the mechanism of action of deoxyribonuclease I

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10493579

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of divalent cations on the reduction and re-formation of the disulfide bonds of deoxyribonuclease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10493579

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Efficacy and safety of short-term administration of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10493579

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1110/PS.8.9.1780

1 reference

24 September 2017

1 reference

PMC publication ID

2144401

24 September 2017

PubMed publication ID

10493579

1 reference

PMC publication ID

2144401