Polygenic disease: methods for mapping complex disease traits (Q40930127)

24 September 2017

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title

Polygenic disease: methods for mapping complex disease traits (English)

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24 September 2017

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2

Lathrop GM

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24 September 2017

Weeks DE

1

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24 September 2017

1 December 1995

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24 September 2017

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24 September 2017

11

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24 September 2017

12

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24 September 2017

513-519

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Genetic dissection of complex traits

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Effect of genetic architecture on the power of human linkage studies to resolve the contribution of quantitative trait loci

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Detection of linkage under heterogeneity: Comparison of the two-locus vs. admixture models

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A genome-wide search for human type 1 diabetes susceptibility genes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Positional cloning moves from perditional to traditional

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Autism as a strongly genetic disorder: evidence from a British twin study

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A case-control family history study of autism

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

HLA-linked genetic control of host response to Mycobacterium leprae

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A further note on the sib-pair linkage method

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A comparison of three affected-sib-pair scoring methods to detect HLA-linked disease susceptibility genes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

The generalized sib pair IBD distribution: its use in the detection of linkage

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A comparison of sib-pair linkage tests for disease susceptibility loci

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Sib-pair linkage tests for disease susceptibility loci: common tests vs. the asymptotically most powerful test

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A powerful test of sib-pair linkage for disease susceptibility.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

The investigation of linkage between a quantitative trait and a marker locus

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Power of affected sibling method tests for linkage.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

There is more than one way to collect data for linkage analysis. What a study of epilepsy can tell us about linkage strategy for psychiatric disease

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

The affected-pedigree-member method: power to detect linkage

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Linkage detection by the Affected-Pedigree-Member method: what is really tested?

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Alzheimer's disease: a piscatorial trek.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Linkage of the Angiotensinogen Gene to Essential Hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Evidence for a susceptibility locus for schizophrenia on chromosome 6pter-p22

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Statistical validity of the Haseman-Elston sib-pair test in small samples.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Linkage between quantitative trait and marker loci: methods using all relative pairs.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Some empirical properties of an all-relative-pairs linkage test

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A more powerful robust sib-pair test of linkage for quantitative traits.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Molecular basis of human hypertension: role of angiotensinogen

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

The angiotensin I-converting enzyme gene polymorphism: implication in hypertension and myocardial infarction.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

The genetic basis of hypertension.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

On the statistical determination of major gene mechanisms in continuous human traits: regressive models.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A note on the basis of regressive models for genetic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Genetic epidemiology of complex phenotypes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Combined segregation and linkage analysis of late-onset Alzheimer's disease in Duke families using Gibbs sampling.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Numerical comparisons of two formulations of the logistic regressive models with the mixed model in segregation analysis of discrete traits

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Use of the regressive models in linkage analysis of quantitative traits

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Robust methods for the detection of genetic linkage for quantitative data from pedigrees

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Extreme discordant sib pairs for mapping quantitative trait loci in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Locating human quantitative trait loci: guidelines for the selection of sibling pairs for genotyping

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Robust multipoint linkage analysis: an extension of the Haseman-Elston method.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Association versus linkage studies in psychosis genetics

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Association and linkage: complementary strategies for complex disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Alcoholism and alleles of the human D2 dopamine receptor locus. Studies of association and linkage

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

The diastrophic dysplasia gene encodes a novel sulfate transporter: positional cloning by fine-structure linkage disequilibrium mapping

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Linkage disequilibrium mapping in isolated founder populations: diastrophic dysplasia in Finland

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A gene for congenital, recessive deafness DFNB3 maps to the pericentromeric region of chromosome 17.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Dominant inheritance in two families with familial Mediterranean fever (FMF)

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Statistical properties of the haplotype relative risk

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A haplotype-based 'haplotype relative risk' approach to detecting allelic associations.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

Delineation of genetic predisposition to multifactorial disease: a general approach on the threshold of feasibility

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

The turning point in genome research

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

A method for constructing radiation hybrid maps of whole genomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-9525%2800%2989163-5

7 January 2021

10.1016/S0168-9525(00)89163-5

Identifiers

DOI

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24 September 2017

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PubMed ID

8533170