The role of the integrin vitronectin receptor, alpha v beta 3 in melanoma metastasis (Q40939420)

25 September 2017

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title

The role of the integrin vitronectin receptor, alpha v beta 3 in melanoma metastasis (English)

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25 September 2017

J Nip

1

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PubMed ID

8548872

25 September 2017

P Brodt

series ordinal

2

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25 September 2017

1 September 1995

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Cancer and Metastasis Reviews

25 September 2017

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25 September 2017

14

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25 September 2017

3

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25 September 2017

241-252

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https://scigraph.springernature.com/pub.10.1007/bf00690295

25 September 2017

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12 December 2020

Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

12 December 2020

Affinity of integrins for damaged extracellular matrix: alpha v beta 3 binds to denatured collagen type I through RGD sites

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12 December 2020

Generation of cell surface-bound plasmin by cell-associated urokinase-type or secreted tissue-type plasminogen activator: a key event in melanoma cell invasiveness in vitro

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12 December 2020

TGF-beta 1 stimulates expression of keratinocyte integrins during re-epithelialization of cutaneous wounds

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12 December 2020

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

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12 December 2020

Granulocyte-macrophage and macrophage colony-stimulating factors differentially regulate alpha v integrin expression on cultured human macrophages

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12 December 2020

Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-beta to TGF-beta

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12 December 2020

Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin

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12 December 2020

Internalization of the urokinase-plasminogen activator inhibitor type-1 complex is mediated by the urokinase receptor

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12 December 2020

Role of growth factors and their receptors in the development and progression of melanoma

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12 December 2020

The plasminogen activator/plasmin system

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12 December 2020

Association of insulin receptor substrate-1 with integrins

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12 December 2020

Plasminogen activator inhibitors--a review

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12 December 2020

Binding of urokinase to its receptor promotes migration and invasion of human melanoma cells in vitro

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12 December 2020

Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

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12 December 2020

Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes

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12 December 2020

Protein-kinase-C inhibitor calphostin C reduces B16 amelanotic melanoma cell adhesion to endothelium and lung colonization

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12 December 2020

Antigenic profile of tumor progression stages in human melanocytic nevi and melanomas

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12 December 2020

The progression associated antigen MUC18: a unique member of the immunoglobulin supergene family

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12 December 2020

Urokinase and urokinase receptor: a paracrine/autocrine system regulating cell migration and invasiveness

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12 December 2020

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression

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12 December 2020

Urokinase-receptor biosynthesis, mRNA level and gene transcription are increased by transforming growth factor beta 1 in human A549 lung carcinoma cells

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12 December 2020

Coordinated expression of the vitronectin receptor and the urokinase-type plasminogen activator receptor in metastatic melanoma cells

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12 December 2020

Plasminogen Activator Released as Inactive Proenzyme from Murine Cells Transformed by Sarcoma Virus

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12 December 2020

Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas

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12 December 2020

Identification of a melanoma progression antigen as integrin VLA-2.

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12 December 2020

Upregulation of urokinase receptor expression on migrating endothelial cells

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12 December 2020

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity

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12 December 2020

Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction

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12 December 2020

Specific roles of the alpha V beta 1, alpha V beta 3 and alpha V beta 5 integrins in avian neural crest cell adhesion and migration on vitronectin

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12 December 2020

Urokinase plasminogen activator (uPA) and its type 1 inhibitor (PAI-1): regulators of proteolysis during cancer invasion and prognostic parameters in breast cancer

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12 December 2020

Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen

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12 December 2020

Adhesive interactions in angiogenesis and metastatasis

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12 December 2020

Urokinase-type plasminogen activator and its inhibitor secreted by cultured human monocyte-macrophages

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12 December 2020

Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity

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12 December 2020

A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma

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12 December 2020

Constitutive alpha V beta 3 integrin-mediated adhesion of human lymphoid B cells to vitronectin substrate.

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12 December 2020

Human melanoma: development and progression

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12 December 2020

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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12 December 2020

Identification of the urokinase receptor as an adhesion receptor for vitronectin

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12 December 2020

IL-3-dependent mast cells attach to plate-bound vitronectin. Demonstration of augmented proliferation in response to signals transduced via cell surface vitronectin receptors

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12 December 2020

Two human melanoma cell-line variants with enhanced in vivo tumor growth and metastatic capacity do not express the beta 3 integrin subunit

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12 December 2020

Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption

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12 December 2020

Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors

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12 December 2020

Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer. Malignant melanoma as a paradigm

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12 December 2020

1 reference

12 December 2020

The plasminogen-plasmin system in malignancy

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12 December 2020

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

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12 December 2020

Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans

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12 December 2020

Interactions between type 1 plasminogen activator inhibitor, extracellular matrix and vitronectin

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12 December 2020

Integrin expression in human melanoma cell lines: heterogeneity of vitronectin receptor composition and function

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12 December 2020

Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression

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12 December 2020

Engagement of the vitronectin receptor (alpha V beta 3) on murine T cells stimulates tyrosine phosphorylation of a 115-kDa protein

1 reference

12 December 2020

Plasminogen activators, their inhibitors, and urokinase receptor emerge in late stages of melanocytic tumor progression

1 reference

12 December 2020

Tumor cell interactions with the extracellular matrix during invasion and metastasis

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12 December 2020

Plasminogen Activation by Receptor-Bound Urokinase

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12 December 2020

The function and distinctive regulation of the integrin VLA-3 in cell adhesion, spreading, and homotypic cell aggregation

1 reference

12 December 2020

Transforming growth factor beta production and responsiveness in normal human melanocytes and melanoma cells

1 reference

12 December 2020

Biology and biochemistry of proteinases in tumor invasion.

1 reference

12 December 2020

The biologic forms of malignant melanoma

1 reference

12 December 2020

Adhesion molecules: novel molecular tools in tumor pathology

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12 December 2020

1 reference

12 December 2020

Identification of a role of the vitronectin receptor and protein kinase C in the induction of endothelial cell vascular formation

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12 December 2020

Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy

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12 December 2020

The alpha v beta 3 integrin associates with a 190-kDa protein that is phosphorylated on tyrosine in response to platelet-derived growth factor

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12 December 2020

Plasminogen activation in melanocytic neoplasia

1 reference

12 December 2020

Expression of vitronectin receptor on human NK cells and its role in protein phosphorylation, cytokine production, and cell proliferation

1 reference

12 December 2020

Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface

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12 December 2020

Adhesion molecules in cancer: the role of integrins.

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12 December 2020

Adhesion mechanisms in lymphatic metastasis

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12 December 2020

Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells

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12 December 2020

Post-receptor occupancy events in leukocytes during beta 1 integrin-ligand interactions.

1 reference

12 December 2020

Growth factor independence and growth regulatory pathways in human melanoma development

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12 December 2020

Role of V Integrins and Vitronectin in Human Melanoma Cell Growth

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12 December 2020

Vitronectin (serum spreading factor): its localisation in normal and fibrotic tissue

1 reference

12 December 2020

Cancer progression and growth: relationship of paracrine and autocrine growth mechanisms to organ preference of metastasis

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12 December 2020

Vitronectin receptor: tissue specific expression or adaptation to culture?

1 reference

12 December 2020

Cell adhesion molecules of the immunoglobulin supergene family and their role in malignant transformation and progression to metastatic disease

1 reference

12 December 2020

Stimulation of migration of human aortic smooth muscle cells by vitronectin: implications for atherosclerosis

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12 December 2020

Cellular receptors for the plasminogen activators

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12 December 2020

Integrin expression in human melanoma cells with differing invasive and metastatic properties

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12 December 2020

Role of the alpha v beta 3 integrin in human melanoma cell invasion

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12 December 2020

Cytokines, growth factors and the loss of negative growth controls in the progression of human cutaneous malignant melanoma

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12 December 2020

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen

1 reference

12 December 2020

Role of integrins and other cell adhesion molecules in tumor progression and metastasis

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12 December 2020

Integrin expression in cutaneous malignant melanoma: association of the alpha 3/beta 1 heterodimer with tumor progression

1 reference

12 December 2020

Vitronectin and its receptors

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12 December 2020

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

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12 December 2020

Beta 1 and beta 3 integrins have different roles in the adhesion and migration of vascular smooth muscle cells on extracellular matrix

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12 December 2020

Basement-membrane components associated with the extracellular matrix of the lymph node

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12 December 2020

Immunological identity of heparin-dependent plasma and urinary protein C inhibitor and plasminogen activator inhibitor-3.

1 reference

12 December 2020

Plasminogen activator inhibitor type I stabilizes vitronectin-dependent adhesions in HT-1080 cells

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12 December 2020

Tumour progression and the nature of cancer

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12 December 2020

Identifiers

DOI

10.1007/BF00690295

1 reference

PubMed ID

8548872

Dimensions Publication ID

25 September 2017

0 references

1 reference

PubMed ID

8548872