Human T-cell receptor variable gene segment families (Q40940163)

25 September 2017

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title

Human T-cell receptor variable gene segment families (English)

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25 September 2017

B Arden

1

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25 September 2017

S P Clark

series ordinal

2

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25 September 2017

D Kabelitz

series ordinal

3

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25 September 2017

T W Mak

series ordinal

4

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25 September 2017

language of work or name

English

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publication date

1 January 1995

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25 September 2017

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25 September 2017

42

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25 September 2017

6

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25 September 2017

455-500

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Amino acid sequences of seven V beta, eight V alpha, and thirteen J alpha novel human TCR genes.

25 September 2017

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12 December 2020

The genomic structure of human V beta 6 T cell antigen receptor genes

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12 December 2020

TCR gene segments from at least one third of V alpha subfamilies rearrange at the delta locus.

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12 December 2020

The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

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12 December 2020

Comparison of human and mouse T-cell receptor variable gene segment subfamilies

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12 December 2020

Heterogeneity of T cells specific for a particular peptide/HLA-DQ complex.

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12 December 2020

Analysis of human T-cell receptor alpha-chain cDNAs isolated from peripheral blood mononuclear cells

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12 December 2020

A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci

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12 December 2020

Further evidence for a gamma/delta T cell receptor-mediated TCT.1/CD48 recognition

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12 December 2020

Allelic sequence variations in the hypervariable region of a T-cell receptor beta chain: correlation with restriction fragment length polymorphism in human families and populations

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12 December 2020

The antigen receptor of an autoreactive T-cell clone from human rheumatic synovia.

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12 December 2020

Repertoire of the human T cell gamma genes: high frequency of nonfunctional transcripts in thymus and mature T cells

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12 December 2020

Molecular analysis of a t(14;14) translocation in leukemic T-cells of an ataxia telangiectasia patient

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12 December 2020

The EMBL Network File Server

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12 December 2020

The human T-cell receptor gamma (TRG) genes

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12 December 2020

Identification and sequence of a fourth human T cell antigen receptor chain

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12 December 2020

Coding region polymorphisms of human T-cell receptor V beta 6.9 and V beta 21.4.

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12 December 2020

Biased T cell receptor V alpha region repertoire in the synovial fluid of rheumatoid arthritis patients

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12 December 2020

Allelic polymorphism of human T-cell receptor V alpha gene segments.

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12 December 2020

Beta-chain gene rearrangements and V beta gene usage in DPw2-specific T cells.

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12 December 2020

Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor

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12 December 2020

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

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12 December 2020

Detection of human T cell receptor cDNAs (alpha, beta, gamma and delta) by ligation of a universal adaptor to variable region

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12 December 2020

Mouse T-cell receptor variable gene segment families

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12 December 2020

Generation of diversity of the beta chain of the human T-lymphocyte receptor for antigen

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12 December 2020

A new method for predicting signal sequence cleavage sites

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12 December 2020

Characterization of an expressed CD3-associated Ti gamma-chain reveals C gamma domain polymorphism

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12 December 2020

Studies on the human T cell receptor α/β variable region genes. II. Identification of four additional Vβ subfamilies

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12 December 2020

Polymorphisms in the Tcrb-V2 gene segments localize the Tcrb orphon genes to human chromosome 9p21.

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12 December 2020

Characterization of the human T cell receptor alpha-chain repertoire and demonstration of a genetic influence on V alpha usage.

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12 December 2020

Gene for alpha-chain of human T-cell receptor: location on chromosome 14 region involved in T-cell neoplasms

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12 December 2020

Profound alteration in an alpha beta T-cell antigen receptor repertoire due to polymorphism in the first complementarity-determining region of the beta chain

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12 December 2020

Rearrangement of two distinct T-cell gamma-chain variable-region genes in human DNA.

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12 December 2020

Unusual forms of T cell gamma mRNA in a human T cell leukemia cell line: implications for gamma gene expression

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12 December 2020

Diversity and structure of human T-cell receptor alpha-chain variable region genes

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12 December 2020

Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups.

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12 December 2020

Analysis of a human V beta gene subfamily

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12 December 2020

Further analysis of the T cell receptor gamma/delta+ peripheral lymphocyte subset. The V delta 1 gene segment is expressed with either C alpha or C delta

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12 December 2020

Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor alpha-chain.

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12 December 2020

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody.

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12 December 2020

Restriction of the T-cell receptor V delta gene repertoire is due to preferential rearrangement and is independent of antigen selection.

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12 December 2020

T-cell antigen receptor genes and T-cell recognition

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12 December 2020

Two autologous melanoma-specific and MHC-restricted human T cell clones with identical intra-tumour reactivity do not share the same TCR V alpha and V beta gene families

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12 December 2020

Thymic ontogeny and selection of alpha beta and gamma delta T cells

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12 December 2020

Human T-cell receptor TCRAV, TCRBV, and TCRAJ sequences newly found in T-cell clones reactive with allogeneic HLA class II antigens.

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12 December 2020

Sequence and expression of transcripts of the human T-cell receptor beta-chain genes.

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12 December 2020

The complete primary structure of the T-cell receptor genes from an alloreactive cytotoxic human T-lymphocyte clone

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12 December 2020

Sequences and repertoire of human T cell receptor alpha chain variable region genes in mature T lymphocytes

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12 December 2020

Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes

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12 December 2020

Human T-cell-receptor delta chain: genomic organization, diversity, and expression in populations of cells

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12 December 2020

Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line

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12 December 2020

Silent allelic variants of a T-cell receptor V beta 12 gene are present in diverse human populations

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12 December 2020

Nonrandom T cell receptor usage in the allorecognition of HLA-DR1 microvariation.

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12 December 2020

Diversity and organization of human T cell receptor delta variable gene segments

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12 December 2020

Identification and physical mapping of a polymorphic human T cell receptor V beta gene with a frequent null allele

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12 December 2020

The mechanism of chromosome 14 inversion in a human T cell lymphoma.

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12 December 2020

Structure and diversity of the human T-cell receptor beta-chain variable region genes

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12 December 2020

Complexity of human T-cell antigen receptor β-chain constant- and variable-region genes

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12 December 2020

Nucleotide sequence of a cDNA corresponding to a new human variable region of a functionally rearranged T cell receptor gamma chain

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12 December 2020

Fusion of an immunoglobulin variable gene and a T cell receptor constant gene in the chromosome 14 inversion associated with T cell tumors.

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12 December 2020

Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes

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12 December 2020

Structure of the gamma/delta T cell receptor of a human thymocyte clone

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12 December 2020

Human T-cell gamma genes contain N segments and have marked junctional variability.

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12 December 2020

In vivo clonal dominance and limited T-cell receptor usage in human CD4+ T-cell recognition of house dust mite allergens

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12 December 2020

Generation of monoclonal antibodies against soluble human T cell receptor polypeptides

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12 December 2020

Partial primary structure of the alpha and beta chains of human tumor T-cell receptors.

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12 December 2020

Organization and orientation of a human T cell receptor delta chain V gene segment that suggests an inversion mechanism is utilized in its rearrangement

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12 December 2020

Structure, organization and polymorphism of murine and human T-cell receptor alpha and beta chain gene families

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12 December 2020

Unexpected consistent involvement of V beta gene segments in inappropriate T-cell receptor beta gene rearrangements occurring in B-lineage acute lymphoblastic leukemias

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12 December 2020

Human T-cell receptor Vα gene polymorphism

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12 December 2020

Sequences and diversity of human T cell receptor beta chain variable region genes

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12 December 2020

Use of a variable alpha region to create a functional T-cell receptor delta chain

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12 December 2020

T cell receptor gamma cDNA in human fetal liver and thymus: variable regions of gamma chains are restricted to V gamma I or V9, due to the absence of splicing of the V10 and V11 leader intron.

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12 December 2020

A nomenclature to fit the organization of the human T-cell receptor gamma and delta genes

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12 December 2020

CDR3 length in antigen-specific immune receptors

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12 December 2020

MALIGNED: a multiple sequence alignment editor

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12 December 2020

T cell receptor alpha chain genes are located on chromosome 14 at 14q11-14q12 in humans

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12 December 2020

Oligoclonal T cells in rheumatoid arthritis: identification strategy and molecular characterization of a clonal T-cell receptor.

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12 December 2020

Organization of human T-cell receptor beta-chain genes: clusters of V beta genes are present on chromosomes 7 and 9.

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12 December 2020

Rearrangement and expression of T-cell antigen receptor genes in human T-lymphocyte tumor lines and normal human T-cell clones: evidence for allelic exclusion of Ti beta gene expression and preferential use of a J beta 2 gene segment

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12 December 2020

Subgroups of variable region genes of beta chains of T-cell receptors for antigen

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12 December 2020

Secretion of disulfide-linked human T-cell receptor gamma delta heterodimers.

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12 December 2020

Allelic variations in the human T cell receptor V beta 6.7 gene products

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12 December 2020

Identification of novel human T-cell receptor V beta gene segments by the anchored-polymerase chain reaction

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12 December 2020

Characterization of a novel human T cell receptor beta chain variable region family by transspecies DNA hybridization.

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12 December 2020

The extent of the human germline T-cell receptor V beta gene segment repertoire

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12 December 2020

Studies on the human T cell receptor α/β variable region genes. I. Identification of 7 additional Vα subfamilies and 14 Jα gene segments

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12 December 2020

A comprehensive set of sequence analysis programs for the VAX

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12 December 2020

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire

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12 December 2020

The T cell receptor beta chain genes are located on chromosome 6 in mice and chromosome 7 in humans

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12 December 2020

Molecular analysis of T-cell receptor transcripts in a human T-cell leukemia bearing a t(1;14) and an inv(7); cell surface expression of a TCR-beta chain in the absence of alpha chain.

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12 December 2020

Evidence for expression of two distinct T cell receptor beta-chain transcripts in a human diphtheria toxoid-specific T cell clone

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12 December 2020

Human T cell clones reactive against U-small nuclear ribonucleoprotein autoantigens from connective tissue disease patients and healthy individuals.

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12 December 2020

The V gamma locus of the human T cell receptor gamma gene. Repertoire polymorphism of the first variable gene segment subgroup

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12 December 2020

The EMBL data library.

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12 December 2020

Subgroups of Tcr alpha chains and correlation with T-cell function

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12 December 2020

Reciprocal hybrid joints demonstrate successive V - J rearrangements on the same chromosome in the human TCR gamma locus

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12 December 2020

T-cell receptor beta-chain gene usage in the T-cell recognition of Mycobacterium leprae antigens in one tuberculoid leprosy patient

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12 December 2020

A soluble, single-chain T-cell receptor fragment endowed with antigen-combining properties

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12 December 2020

Reduced expression of a human V beta 6.1 T-cell receptor allele

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12 December 2020

Nucleotide sequence analysis of 77.7 kb of the human V beta T-cell receptor gene locus: direct primer-walking using cosmid template DNAs

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12 December 2020

Sequence and evolution of the human T-cell antigen receptor beta-chain genes

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12 December 2020

Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain

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12 December 2020

Systematic study of human alpha beta T cell receptor V segments shows allelic variations resulting in a large number of distinct T cell receptor haplotypes.

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12 December 2020

Frequent recombination in the human T-cell receptor beta gene complex

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12 December 2020

Abnormal recombination products result from aberrant DNA rearrangement of the human T-cell antigen receptor beta-chain gene

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12 December 2020

Complex rearrangements within the human J delta-C delta/J alpha-C alpha locus and aberrant recombination between J alpha segments.

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12 December 2020

Human T-cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32.

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12 December 2020

The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia

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12 December 2020

Genomically imposed and somatically modified human thymocyte V beta gene repertoires

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12 December 2020

Asymmetric selection of T cell antigen receptor alpha- and beta-chains in HLA-B27 alloreactivity

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12 December 2020

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12 December 2020

The breakpoint of an inversion of chromosome 14 in a T-cell leukemia: sequences downstream of the immunoglobulin heavy chain locus are implicated in tumorigenesis

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12 December 2020

The human T cell receptor beta-chain gene complex contains at least 57 variable gene segments. Identification of six V beta genes in four new gene families

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12 December 2020

Primary structure of human T-cell receptor alpha-chain

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12 December 2020

First genomic sequence of the human T-cell receptor delta 2 gene (TRDV2).

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12 December 2020

Germline sequence of two human T-cell receptor V beta genes: V beta 8.1 is transcribed from a TATA-box promoter.

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12 December 2020

Human Tcrb-V6.10 is a pseudogene with Alu repetitive sequences in the promoter region.

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12 December 2020

A joining-diversity-joining complex generated by inversion mechanism and a variable-diversity complex in the beta-chain gene of the human T-cell receptor

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12 December 2020

Sequences and repertoire of the human T cell receptor alpha and beta chain variable region genes in thymocytes

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12 December 2020

Diversity and structure of human T-cell receptor beta-chain variable region genes

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12 December 2020

Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus.

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12 December 2020

Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes

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12 December 2020

Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility co

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12 December 2020

Variability in T cell receptor V beta gene usage in human peripheral blood lymphocytes. Studies of identical twins, siblings, and insulin-dependent diabetes mellitus patients

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12 December 2020

Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors

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12 December 2020

Promoter and enhancer elements in the rearranged alpha chain gene of the human T cell receptor.

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12 December 2020

Novel members and germline polymorphisms in the human T-cell receptor Vb6 family.

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12 December 2020

Antibody framework residues affecting the conformation of the hypervariable loops

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12 December 2020

The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA.

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12 December 2020

Polymorphism detection and sequence analysis of human T-cell receptor V alpha-chain-encoding gene segments

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12 December 2020

Genomic organization of the human T-cell antigen-receptor alpha/delta locus

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12 December 2020

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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12 December 2020

Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution

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12 December 2020

Sequences of four previously undescribed human T-cell receptor β chain variable genes

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12 December 2020

Identification of putative human T cell receptor delta complementary DNA clones

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12 December 2020

Sequence and expression of a novel human T-cell receptor beta-chain variable gene segment subfamily

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12 December 2020

The outline structure of the T-cell alpha beta receptor.

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12 December 2020

Polymerase chain reaction with single-sided specificity: analysis of T cell receptor delta chain.

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12 December 2020

New subgroups in the human T cell rearranging V gamma gene locus

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12 December 2020

Characterization of a third form of the human T cell receptor gamma/delta

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12 December 2020

New human V beta genes and polymorphic variants

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12 December 2020

Differentiation in mature T lymphoid leukemia cells is unstable and reversible to myeloid cells, without the involvement of a common stem cell

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12 December 2020

Genes of the T-cell antigen receptor in normal and malignant T cells

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12 December 2020

Few V gene segments dominate the T cell receptor beta-chain repertoire of the human thymus

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12 December 2020

Measuring the human T cell receptor gamma-chain locus

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12 December 2020

Analysis of DNA surrounding the breakpoints of chromosomal translocations involving the beta T cell receptor gene in human lymphoblastic neoplasms.

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12 December 2020

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