Interleukin-6 (IL-6) production by astrocytes: autocrine regulation by IL-6 and the soluble IL-6 receptor. (Q40946726)

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9 December 2019

title

Interleukin-6 (IL-6) production by astrocytes: autocrine regulation by IL-6 and the soluble IL-6 receptor (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10377335%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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N J Van Wagoner

1

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9 December 2019

J W Oh

series ordinal

2

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9 December 2019

P Repovic

series ordinal

3

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9 December 2019

E N Benveniste

series ordinal

4

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9 December 2019

language of work or name

English

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publication date

1 July 1999

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9 December 2019

published in

Journal of Neuroscience

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9 December 2019

volume

19

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9 December 2019

issue

13

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9 December 2019

page(s)

5236-5244

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Cytokine actions in the central nervous system

9 December 2019

cites work

1 reference

12 December 2020

Oncostatin M and the interleukin-6 and soluble interleukin-6 receptor complex regulate alpha1-antichymotrypsin expression in human cortical astrocytes.

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The soluble interleukin-6 receptor is generated by shedding

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Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8

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Activation of gp 130 by IL-6/soluble IL-6 receptor induces neuronal differentiation

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IL-1 and tumor necrosis factor synergistically stimulate fibroblast IL-6 production and stabilize IL-6 messenger RNA.

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Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma

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A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family

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Role of protein kinase C activity in tumor necrosis factor-alpha gene expression. Involvement at the transcriptional level

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The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

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Transcriptional roles of CCAAT/enhancer binding protein-beta, nuclear factor-kappaB, and C-promoter binding factor 1 in interleukin (IL)-1beta-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes

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12 December 2020

Post-transcriptional stabilization by interleukin-1beta of interleukin-6 mRNA induced by c-kit ligand and interleukin-10 in mouse bone marrow-derived mast cells

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12 December 2020

TGF-beta suppresses IFN-gamma induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression.

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12 December 2020

Release of the soluble interleukin-6 receptor from human T-cells

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12 December 2020

Sympathetic neurons can produce and respond to interleukin 6

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12 December 2020

Interleukin-1β induction of tumor necrosis factor-alpha gene expression in human astroglioma cells

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12 December 2020

Shedding of the soluble IL-6 receptor is triggered by Ca2+ mobilization, while basal release is predominantly the product of differential mRNA splicing in THP-1 cells

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12 December 2020

Interleukin-6 as a neurotrophic factor for promoting the survival of cultured basal forebrain cholinergic neurons from postnatal rats

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12 December 2020

Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

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12 December 2020

Differential modulation of astrocyte cytokine gene expression by TGF-beta

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12 December 2020

Physiological and pathological roles of interleukin-6 in the central nervous system

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12 December 2020

Interleukin 6 is autoregulated by transcriptional mechanisms in cultures of rat osteoblastic cells

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12 December 2020

Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor

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12 December 2020

Interleukin-6 (IL-6) and its soluble receptor support survival of sensory neurons

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12 December 2020

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

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12 December 2020

Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat.

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12 December 2020

Interferon-gamma regulation of C3 gene expression in human astroglioma cells

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12 December 2020

Intercellular adhesion molecule-1 gene expression by glial cells. Differential mechanisms of inhibition by IL-10 and IL-6

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12 December 2020

Differential regulation of astrocyte TNF-alpha expression by the cytokines TGF-beta, IL-6 and IL-10

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12 December 2020

Cytokine-induced expression of vascular cell adhesion molecule-1 (VCAM-1) by astrocytes and astrocytoma cell lines

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12 December 2020

Interleukin-6 (IL-6)--a molecule with both beneficial and destructive potentials

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12 December 2020

Regulation of intercellular adhesion molecule-1 gene expression by tumor necrosis factor-alpha, interleukin-1 beta, and interferon-gamma in astrocytes

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12 December 2020

Cytokines: influence on glial cell gene expression and function

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12 December 2020

Gp130 and the interleukin-6 family of cytokines

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12 December 2020

Induction and regulation of interleukin-6 gene expression in rat astrocytes

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12 December 2020

Stat1 alpha expression is involved in IFN-gamma induction of the class II transactivator and class II MHC genes

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12 December 2020

Concerted participation of NF-kappa B and C/EBP heteromer in lipopolysaccharide induction of serum amyloid A gene expression in liver

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12 December 2020

Oncostatin M binds directly to gp130 and behaves as interleukin-6 antagonist on a cell line expressing gp130 but lacking functional oncostatin M receptors

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12 December 2020

Soluble interleukin 6 receptor in biological fluids from human origin

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12 December 2020

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

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12 December 2020

Interleukin-6 production by astrocytes: induction by the neurotransmitter norepinephrine

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12 December 2020

Involvement of cytokines in normal CNS development and neurological diseases: recent progress and perspectives

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12 December 2020

Role of IL-6 and the soluble IL-6 receptor in inhibition of VCAM-1 gene expression.

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12 December 2020

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

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12 December 2020

Altered physiology of Purkinje neurons in cerebellar slices from transgenic mice with chronic central nervous system expression of interleukin-6.

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12 December 2020

Cytokine regulation of interleukin-6 gene expression in astrocytes involves activation of an NF-κ B-like nuclear protein

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12 December 2020

Inflammation in EAE: role of chemokine/cytokine expression by resident and infiltrating cells

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12 December 2020

Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6

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12 December 2020

Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6.

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12 December 2020

Impaired neuroglial activation in interleukin-6 deficient mice.

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12 December 2020

Soluble receptors for cytokines and growth factors: generation and biological function

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12 December 2020

Oncostatin M and leukemia inhibitory factor trigger overlapping and different signals through partially shared receptor complexes

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12 December 2020

Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B

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12 December 2020

10.1523/JNEUROSCI.19-13-05236.1999

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10377335%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10377335%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

PubMed publication ID

10377335

1 reference