The proto-oncogene c-Cbl is a negative regulator of DNA synthesis initiated by both receptor and cytoplasmic tyrosine kinases (Q40949624)

25 September 2017

The proto-oncogene c-Cbl is a negative regulator of DNA synthesis initiated by both receptor and cytoplasmic tyrosine kinases (English)

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25 September 2017

3

J Schlessinger

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25 September 2017

M A Broome

1

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25 September 2017

M L Galisteo

series ordinal

2

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25 September 2017

S A Courtneidge

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4

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25 September 2017

language of work or name

English

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publication date

1 May 1999

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25 September 2017

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25 September 2017

18

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25 September 2017

18

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25 September 2017

2908-2912

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1202873

25 September 2017

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cites work

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Association between the PDGF receptor and members of the src family of tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

A mechanism for regulation of the adhesion-associated proteintyrosine kinase pp125FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

The Cbl family of signal transduction molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

A functional screen in yeast for regulators and antagonizers of heterologous protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

EGF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans sli-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

7 January 2021

The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

7 January 2021

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

7 January 2021

Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202873

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202873

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Dimensions Publication ID

25 September 2017

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