Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity. (Q40949673)

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8 December 2019

title

Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity (English)

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8 December 2019

1

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8 December 2019

Maurizio D'Incalci

6

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8 December 2019

Massimo Broggini

7

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8 December 2019

author name string

Cirò M

2

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8 December 2019

Gallinari F

3

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8 December 2019

Geroni C

4

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8 December 2019

Cozzi P

5

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8 December 2019

language of work or name

English

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publication date

1 June 1999

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British Journal of Cancer

8 December 2019

published in

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8 December 2019

volume

80

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8 December 2019

issue

7

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8 December 2019

page(s)

991-997

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DNA minor groove binding ligands: a new class of anticancer agents

8 December 2019

cites work

1 reference

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Estimation of the haematological toxicity of minor groove alkylators using tests on human cord blood cells

25 September 2017

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Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53.

25 September 2017

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Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53

25 September 2017

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DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin

25 September 2017

1 reference

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DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards

25 September 2017

1 reference

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DNA sequence specificity of antitumor agents. Oncogenes as possible targets for cancer therapy

25 September 2017

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Measurement of the sequence specificity of covalent DNA modification by antineoplastic agents using Taq DNA polymerase

25 September 2017

1 reference

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Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue.

25 September 2017

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Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis

25 September 2017

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Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells

25 September 2017

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Establishment of L1210 leukemia cells resistant to the distamycin-A derivative (FCE 24517): characterization and cross-resistance studies.

25 September 2017

1 reference

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DNA sequence selectivity of guanine-N7 alkylation by three antitumor chloroethylating agents

17 June 2018

1 reference

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Selective DNA interaction of the novel distamycin derivative FCE 24517.

17 June 2018

1 reference

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Sequence-specific DNA interactions by novel alkylating anthracycline derivatives

17 June 2018

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12 December 2020

Reaction of the antitumor antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity

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12 December 2020

Design, synthesis, and biological evaluation of DNA sequence and minor groove selective alkylating agents

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12 December 2020

CC-1065 (NSC 298223), a novel antitumor agent that interacts strongly with double-stranded DNA

1 reference

12 December 2020

DNA-minor-groove alkylators, a new class of anticancer agents

1 reference

12 December 2020

Effect of the (+)-CC-1065-(N3-adenine)DNA adduct on in vitro DNA synthesis mediated by Escherichia coli DNA polymerase

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12 December 2020

Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses

1 reference

12 December 2020

p21WAF1-derived peptides linked to an internalization peptide inhibit human cancer cell growth

1 reference

12 December 2020

Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity

1 reference

12 December 2020

Phase I study of the novel distamycin derivative tallimustine (FCE 24517)

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6690453

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362106%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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8 December 2019

PubMed publication ID

10362106

1 reference