Transgenic mouse models of breast cancer (Q40959643)

25 September 2017

1 reference

title

Transgenic mouse models of breast cancer (English)

1 reference

25 September 2017

L T Amundadottir

1

1 reference

25 September 2017

G Merlino

series ordinal

2

1 reference

25 September 2017

R B Dickson

series ordinal

3

1 reference

25 September 2017

language of work or name

English

0 references

publication date

1 January 1996

1 reference

Breast Cancer Research and Treatment

25 September 2017

published in

1 reference

25 September 2017

volume

39

1 reference

25 September 2017

issue

1

1 reference

25 September 2017

page(s)

119-135

1 reference

Tyrosine kinase activity is essential for the association of phospholipase C-gamma with the epidermal growth factor receptor

25 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

c-erbB-2/c-erbA co-amplification indicative of lymph node metastasis, and c-myc amplification of high tumour grade, in human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

c-erbB-2 oncogene as a prognostic marker in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

Transgenic mice carrying the mouse mammary tumor virus ras fusion gene: distinct effects in various tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01806083

Identification and cloning of two overexpressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas

21 January 2018

1 reference

12 December 2020

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1 reference

12 December 2020

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

12 December 2020

Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas

1 reference

12 December 2020

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

1 reference

12 December 2020

DNA amplification at 11q13.5-q14 in human breast cancer

1 reference

12 December 2020

Neu receptor dimerization

1 reference

12 December 2020

Cyclin E, a potential prognostic marker for breast cancer

1 reference

12 December 2020

BCL-1 participates in the 11q13 amplification found in breast cancer

1 reference

12 December 2020

Cyclin A is required at two points in the human cell cycle

1 reference

12 December 2020

Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1 reference

12 December 2020

Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation

1 reference

12 December 2020

p53 mutations in breast cancer

1 reference

12 December 2020

Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-2 protein overexpression in primary breast cancer

1 reference

12 December 2020

The int-2 gene product acts as an epithelial growth factor in transgenic mice

1 reference

12 December 2020

Absence of activating transmembrane mutations in the c-erbB-2 proto-oncogene in human breast cancer

1 reference

12 December 2020

Function of the c-Myc oncoprotein

1 reference

12 December 2020

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands

1 reference

12 December 2020

Expression of amphiregulin, cripto-1, and heregulin-alpha in human breast-cancer cells

1 reference

12 December 2020

Early and multifocal tumors in breast, salivary, Harderian and epididymal tissues developed in MMTY-Neu transgenic mice

1 reference

12 December 2020

Growth factors from murine sarcoma virus-transformed cells

1 reference

12 December 2020

Preferential overexpression of a 172Arg-->Leu mutant p53 in the mammary gland of transgenic mice results in altered lobuloalveolar development

1 reference

12 December 2020

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

1 reference

12 December 2020

Immunological detection and quantitation of alpha transforming growth factors in human breast carcinoma cells

1 reference

12 December 2020

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

1 reference

12 December 2020

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1 reference

12 December 2020

Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors

1 reference

12 December 2020

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1 reference

12 December 2020

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

1 reference

12 December 2020

Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice

1 reference

12 December 2020

Association of the polyomavirus middle-T antigen with c-yes protein

1 reference

12 December 2020

Mutations in the p53 gene occur in diverse human tumour types

1 reference

12 December 2020

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

12 December 2020

Monoclonal antibodies of predefined specificity detect activated ras gene expression in human mammary and colon carcinomas

1 reference

12 December 2020

Expression of cellular oncogenes in human malignancies

1 reference

12 December 2020

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

1 reference

12 December 2020

Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice

1 reference

12 December 2020

TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1 reference

12 December 2020

Transgenic oncogene mice. Tumor phenotype predicts genotype

1 reference

12 December 2020

Redundant cyclin overexpression and gene amplification in breast cancer cells

1 reference

12 December 2020

Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice

1 reference

12 December 2020

Oncogenes and signal transduction

1 reference

12 December 2020

1 reference

12 December 2020

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1 reference

12 December 2020

Reversible inhibition of mammary gland growth by transforming growth factor-beta

1 reference

12 December 2020

p53 as an independent prognostic marker in lymph node-negative breast cancer patients

1 reference

12 December 2020

Cell biology. Cell cycle gets more cyclins

1 reference

12 December 2020

1 reference

12 December 2020

The role of the epidermal growth factor receptor and the c-erbB-2 protein in breast cancer.

1 reference

12 December 2020

Cut, paste, and save: new approaches to altering specific genes in mice

1 reference

12 December 2020

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

1 reference

12 December 2020

Amplification and expression of the human cyclin D gene in esophageal cancer

1 reference

12 December 2020

Cooperation between oncogenes

1 reference

12 December 2020

Amplified expression of p21 ras protein in hormone-dependent mammary carcinomas of humans and rodents

1 reference

12 December 2020

Expression of pp60c-src protein kinase in adult and fetal human tissue: high activities in some sarcomas and mammary carcinomas.

1 reference

12 December 2020

The 3Rs of life: Ras, Raf and growth regulation

1 reference

12 December 2020

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

1 reference

12 December 2020

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

1 reference

12 December 2020

Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.

1 reference

12 December 2020

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

12 December 2020

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

1 reference

12 December 2020

The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins

1 reference

12 December 2020

Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4.

1 reference

12 December 2020

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1 reference

12 December 2020

In situ c-myc expression and genomic status of the c-myc locus in infiltrating ductal carcinomas of the breast

1 reference

12 December 2020

Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells

1 reference

12 December 2020

Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues

1 reference

12 December 2020

Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription

1 reference

12 December 2020

Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis

1 reference

12 December 2020

Transgenic mice as models for tumorigenesis

1 reference

12 December 2020

Expression and amplification of cyclin genes in human breast cancer

1 reference

12 December 2020

The functions of Myc proteins

1 reference

12 December 2020

Expression of transforming growth factor alpha and its messenger ribonucleic acid in human breast cancer: its regulation by estrogen and its possible functional significance

1 reference

12 December 2020

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1 reference

12 December 2020

c-myc amplification is an independent prognostic factor in postmenopausal breast cancer

1 reference

12 December 2020

In Vivo Amplification and Rearrangement of c-myc Oncogene in Human Breast Tumors

1 reference

12 December 2020

Breast cancer formation in transgenic animals induced by the whey acidic protein SV40 T antigen (WAP-SV-T) hybrid gene

1 reference

12 December 2020

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

12 December 2020

Some recent advances in the chemistry and biology of transforming growth factor-beta

1 reference

12 December 2020

Amphiregulin, epidermal growth factor receptor, and estrogen receptor expression in human primary breast cancer

1 reference

12 December 2020

Genetic alterations of c-myc, c-erbB-2, and c-Ha-ras protooncogenes and clinical associations in human breast carcinomas

1 reference

12 December 2020

Nonuniform expression of a mouse mammary tumor virus-driven int-2/Fgf-3 transgene in pregnancy-responsive breast tumors

1 reference

12 December 2020

Identification of transforming growth factor alpha in human primary breast carcinomas

1 reference

12 December 2020

Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse

1 reference

12 December 2020

Increased erbB-2 gene copies and expression in multiple stages of breast cancer

1 reference

12 December 2020

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1 reference

12 December 2020

Human transforming growth factor-alpha: precursor structure and expression in E. coli

1 reference

12 December 2020

D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1

1 reference

12 December 2020

Loss of a c-H-ras-1 allele and aggressive human primary breast carcinomas

1 reference

12 December 2020

The tumor suppressor genes

1 reference

12 December 2020

Growth factor expression in normal, benign, and malignant breast tissue

1 reference

12 December 2020

Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.

1 reference

12 December 2020

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1 reference

12 December 2020

The neu oncogene encodes an epidermal growth factor receptor-related protein

1 reference

12 December 2020

Amplification of a novel v-erbB-related gene in a human mammary carcinoma

1 reference

12 December 2020

Immunoreactive alpha transforming growth factor activity in effusions from cancer patients as a marker of tumor burden and patient prognosis

1 reference

12 December 2020

Alteration of morphogenesis by the v-myc oncogene in transplants of mammary gland

1 reference

12 December 2020

Regulation of development of the normal mammary gland by hormones and growth factors

1 reference

12 December 2020

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1 reference

12 December 2020

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

1 reference

12 December 2020

The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-gamma

1 reference

12 December 2020

Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product.

1 reference

12 December 2020

Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.

1 reference

12 December 2020

Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development

1 reference

12 December 2020

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

12 December 2020

1 reference

12 December 2020

Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer

1 reference

12 December 2020

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

12 December 2020

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

1 reference

12 December 2020

A novel cyclin encoded by a bcl1-linked candidate oncogene

1 reference

12 December 2020

Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells

1 reference

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

1 reference

12 December 2020

The amplification unit on chromosome 11q13 in aggressive primary human breast tumors entails the bcl-1, int-2 and hst loci

1 reference

12 December 2020

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

1 reference

12 December 2020

Cyclin synthesis, modification and destruction during meiotic maturation of the starfish oocyte

1 reference

12 December 2020

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

1 reference

12 December 2020

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01806083

1 reference

Dimensions Publication ID

25 September 2017

1004870695

0 references

1 reference