Hypoxia post-translationally activates iron-regulatory protein 2. (Q40973622)

25 September 2017

Hypoxia post-translationally activates iron-regulatory protein 2. (English)

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25 September 2017

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Hanson ES

1

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25 September 2017

Foot LM

series ordinal

2

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25 September 2017

Leibold EA

series ordinal

3

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25 September 2017

language of work or name

English

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publication date

1 February 1999

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Journal of Biological Chemistry

25 September 2017

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25 September 2017

274

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25 September 2017

5047-5052

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25 September 2017

8

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

25 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

The hypoxic response: huffing and HIFing

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Post-transcriptional regulation of vascular endothelial growth factor by hypoxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Sequencing of the human vascular endothelial growth factor (VEGF) 3' untranslated region (UTR): conservation of five hypoxia-inducible RNA-protein binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Characterization of the hypoxia-inducible protein binding site within the pyrimidine-rich tract in the 3'-untranslated region of the tyrosine hydroxylase mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Regulation of iron regulatory protein 1 during hypoxia and hypoxia/reoxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

A regulated RNA binding protein also possesses aconitase activity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Iron regulates the intracellular degradation of iron regulatory protein 2 by the proteasome

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Purification and characterization of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Characterization and expression of iron regulatory protein 2 (IRP2). Presence of multiple IRP2 transcripts regulated by intracellular iron levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Oxygen-dependent expression of the erythropoietin gene in rat hepatocytes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Single-step selection of clones of a mouse hepatoma line deficient in aryl hydrocarbon hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Differences in the RNA binding sites of iron regulatory proteins and potential target diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Iron regulatory proteins 1 and 2 bind distinct sets of RNA target sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Loops and bulge/loops in iron-responsive element isoforms influence iron regulatory protein binding. Fine-tuning of mRNA regulation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

The role of thiol oxidation in Cobalt(II)-induced toxicity in hamster lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.8.5047

21 January 2018

Identifiers

DOI

10.1074/JBC.274.8.5047

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25 September 2017

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