Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase (Q40975672)

25 September 2017

Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase (English)

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3'-deoxythymidine 5'-triphosphate

25 September 2017

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1 reference

ChEBI release 2020-05-28

S Eriksson

1

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25 September 2017

B Xu

series ordinal

2

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25 September 2017

D A Clayton

series ordinal

3

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25 September 2017

language of work or name

English

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publication date

1 August 1995

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Journal of Biological Chemistry

25 September 2017

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25 September 2017

270

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25 September 2017

32

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25 September 2017

18929-18934

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Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides

25 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Molecular targets for AIDS therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Mitochondrial myopathy caused by long-term zidovudine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Reversible axonal neuropathy from the treatment of AIDS and related disorders with 2',3'-dideoxycytidine (ddC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Effects of 2',3'-dideoxynucleosides on proliferation and differentiation of human pluripotent progenitors in liquid culture and their effects on mitochondrial DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Ultrastructural changes associated with reduced mitochondrial DNA and impaired mitochondrial function in the presence of 2'3'-dideoxycytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

The 5'-triphosphates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxynucleosides inhibit DNA polymerase gamma by different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Purification and characterization of porcine liver DNA polymerase gamma: utilization of dUTP and dTTP during in vitro DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Studies on Deoxyribonucleic Acid Polymerases from Yeast. 2. Partial Purification and Characterization of Mitochondrial DNA Polymerase from Wild Type and Respiration-Deficient Yeast Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Assignment of a yeast protein necessary for mitochondrial transcription initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Studies on the inhibition of mitochondrial DNA replication by 3'-azido-3'-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.32.18929

21 January 2018

Identifiers

DOI

10.1074/JBC.270.32.18929

1 reference

25 September 2017

1 reference