Regiospecific synthesis and anti-human immunodeficiency virus activity of novel 5-substituted N-alkylcarbamoyl and N,N-dialkylcarbamoyl 1,2,3-triazole-TSAO analogues (Q40985925)

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scientific article published on November 1998

Language	Label	Description	Also known as
English	Regiospecific synthesis and anti-human immunodeficiency virus activity of novel 5-substituted N-alkylcarbamoyl and N,N-dialkylcarbamoyl 1,2,3-triazole-TSAO analogues	scientific article published on November 1998

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Regiospecific synthesis and anti-human immunodeficiency virus activity of novel 5-substituted N-alkylcarbamoyl and N,N-dialkylcarbamoyl 1,2,3-triazole-TSAO analogues (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

5

object named as

E De Clercq

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6

object named as

J Balzarini

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Europe PubMed Central

PubMed publication ID

25 September 2017

author name string

S Velázquez

1

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Europe PubMed Central

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25 September 2017

R Alvarez

2

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Europe PubMed Central

PubMed publication ID

25 September 2017

C Pérez

3

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

F Gago

4

1 reference

Europe PubMed Central

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25 September 2017

M J Camarasa

7

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PubMed publication ID

25 September 2017

publication date

1 November 1998

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25 September 2017

Antiviral Chemistry & Chemotherapy

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25 September 2017

9

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6

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25 September 2017

481-489

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25 September 2017

1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcri

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

[2',5'-Bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of purine and pyrimidinenucleosides as potent and selective inhibitors of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Sensitivity of (138 Glu-->Lys) mutated human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) to HIV-1-specific RT inhibitors

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

HIV-1-specific RT inhibitors: highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Toward improved anti-HIV chemotherapy: therapeutic strategies for intervention with HIV infections

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of human immunodeficiency virus type 1 (HIV-1) infections: strategies to overcome drug resistance development

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular model

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Automated docking of substrates to proteins by simulated annealing

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Automated docking of flexible ligands: applications of AutoDock

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

The retroviral enzymes

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

TSAO analogues. Stereospecific synthesis and anti-HIV-1 activity of 1-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro -5''- (4''-amino-1'',2''-oxathiole 2'',2''-dioxide) pyrimidine and pyrimidine-modified nucleosides

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

High resolution structures of HIV-1 RT from four RT-inhibitor complexes

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

The biochemistry of AIDS.

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

TSAO analogues. 3. Synthesis and anti-HIV-1 activity of 2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl 3'-spiro-5''-(4''-amino-1'',2''-oxathiole 2'',2''-dioxide) purine and purine-modified nucleosides.

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2', 5'-bis-O-(tert-butyldimethylsilyl)-.beta.-D-xylo- and -ribofuranose]-3'-spiro-5''-[4''-amino-1'', 2''-oxathiole 2''

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

TSAO Derivatives: Highly Specific Inhibitors of Human Immunodeficiency Virus Type-1 (HIV-1) Replication

1 reference

https://api.crossref.org/works/10.1177%2F095632029800900604

21 January 2018

Identifiers

10.1177/095632029800900604

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

ResearchGate publication ID

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