Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell (Q41018799)

25 September 2017

Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell (English)

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25 September 2017

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Maechler P

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25 September 2017

Kennedy ED

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2

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25 September 2017

Wang H

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3

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25 September 2017

Wollheim CB

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4

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25 September 2017

language of work or name

English

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publication date

1 August 1998

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Journal of Biological Chemistry

25 September 2017

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25 September 2017

273

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25 September 2017

33

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25 September 2017

20770-20778

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Coupling of beta-cell desensitization by hyperglycemia to excessive stimulation and circulating insulin in glucose-infused rats

25 September 2017

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Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions

21 January 2018

1 reference

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Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Differentiating glucose toxicity from glucose desensitization: a new message from the insulin gene

21 January 2018

1 reference

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Dynamics of Ca2+ and guanosine 5'-[gamma-thio]triphosphate action on insulin secretion from alpha-toxin-permeabilized HIT-T15 cells.

21 January 2018

1 reference

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Metabolic coupling factors in pancreatic beta-cell signal transduction

21 January 2018

1 reference

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Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

New insights into pancreatic beta-cell metabolic signaling in insulin secretion

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Physiological role of mitochondrial Ca2+ transport

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Subcellular imaging of intramitochondrial Ca2+ with recombinant targeted aequorin: significance for the regulation of pyruvate dehydrogenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Hexose metabolism in pancreatic islets. Participation of Ca2(+)-sensitive 2-ketoglutarate dehydrogenase in the regulation of mitochondrial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells

21 January 2018

1 reference

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Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

21 January 2018

1 reference

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Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes

21 January 2018

1 reference

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Substrate-dependent changes in mitochondrial function, intracellular free calcium concentration and membrane channels in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Ca2+-induced exocytosis in individual human neutrophils: high- and low-affinity granule populations and submaximal responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Mitochondrial Ca2+ homeostasis in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Differentiation between glucose-induced desensitization of insulin secretion and beta-cell exhaustion in the HIT-T15 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Calcium activation of mitochondrial glycerol phosphate dehydrogenase restudied

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Essential Ca(2+)-binding motif for Ca(2+)-sensitive inactivation of L-type Ca2+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Feedback inhibition of Ca2+ channels by Ca2+ depends on a short sequence of the C terminus that does not include the Ca2+ -binding function of a motif with similarity to Ca2+ -binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

Inactivation of HIT cell Ca2+ current by a simulated burst of Ca2+ action potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.33.20770

21 January 2018

Identifiers

DOI

10.1074/JBC.273.33.20770

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25 September 2017

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