Effects of mutations within the SV40 large T antigen ATPase/p53 binding domain on viral replication and transformation (Q41038091)

25 September 2017

Effects of mutations within the SV40 large T antigen ATPase/p53 binding domain on viral replication and transformation (English)

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25 September 2017

Peden KW

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25 September 2017

Srinivasan A

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2

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25 September 2017

Vartikar JV

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3

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25 September 2017

Pipas JM

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4

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25 September 2017

1 January 1998

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25 September 2017

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25 September 2017

16

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25 September 2017

2

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25 September 2017

153-165

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https://scigraph.springernature.com/pub.10.1023/a:1007941622680

25 September 2017

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cites work

The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions

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12 December 2020

Local mutagenesis within deletion loops of DNA heteroduplexes

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12 December 2020

Genetic and biochemical analysis of transformation-competent, replication-defective simian virus 40 large T antigen mutants

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12 December 2020

Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53.

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12 December 2020

Common and unique features of T antigens encoded by the polyomavirus group

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12 December 2020

Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens

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12 December 2020

Simian virus 40 large T-antigen point mutants that are defective in viral DNA replication but competent in oncogenic transformation

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12 December 2020

Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant

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12 December 2020

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12 December 2020

Structure and function of simian virus 40 large tumor antigen

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12 December 2020

The ability of large T antigen to complex with p53 is necessary for the increased life span and partial transformation of human cells by simian virus 40.

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12 December 2020

A DNA replication-positive mutant of simian virus 40 that is defective for transformation and the production of infectious virions

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12 December 2020

Deletion mutants of simian virus 40 generated by enzymatic excision of DNA segments from the viral genome

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12 December 2020

Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations

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12 December 2020

Isolation of Mutants of an Animal Virus in Bacteria

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12 December 2020

T-antigen mutant activities in vivo: roles of p53 and pRB binding in tumorigenesis of the choroid plexus

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12 December 2020

The replication functions of SV40 T antigen are regulated by phosphorylation

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12 December 2020

Requirements for immortalization of primary mouse embryo fibroblasts probed with mutants bearing deletions in the 3' end of SV40 gene A

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12 December 2020

Mutational Analysis of Simian Virus 40 T Antigen: Isolation and Characterization of Mutants with Deletions in the T-Antigen Gene

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12 December 2020

Transformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen

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12 December 2020

The ability of simian virus 40 large T antigen to immortalize primary mouse embryo fibroblasts cosegregates with its ability to bind to p53.

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12 December 2020

Mapping temperature-sensitive mutants of simian virus 40: rescue of mutants by fragments of viral DNA.

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12 December 2020

Identifiers

DOI

10.1023/A:1007941622680

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Dimensions Publication ID

25 September 2017

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