Stringent structural requirements for anti-Ras activity of S-prenyl analogues (Q41050673)

26 September 2017

title

Stringent structural requirements for anti-Ras activity of S-prenyl analogues (English)

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26 September 2017

Z Aharonson

1

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26 September 2017

M Gana-Weisz

2

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26 September 2017

T Varsano

3

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26 September 2017

R Haklai

4

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26 September 2017

D Marciano

5

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26 September 2017

Y Kloog

6

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26 September 2017

publication date

1 February 1998

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Biochimica et Biophysica Acta

26 September 2017

published in

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26 September 2017

volume

1406

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26 September 2017

issue

1

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26 September 2017

page(s)

40-50

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The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors.

26 September 2017

cites work

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Blocked Ras activation in anergic CD4+ T cells

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Proteins regulating Ras and its relatives

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p21ras: An oncoprotein functioning in growth factor-induced signal transduction

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7 January 2021

p21ras is modified by a farnesyl isoprenoid

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7 January 2021

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

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7 January 2021

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

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7 January 2021

Activation of Raf as a result of recruitment to the plasma membrane

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7 January 2021

All ras proteins are polyisoprenylated but only some are palmitoylated

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7 January 2021

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

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7 January 2021

Protein prenylation: more than just glue?

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7 January 2021

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

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7 January 2021

Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane

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Unexpectedly strong binding of a large metal ion (Bi3+) to human serum transferrin

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7 January 2021

Farnesyl derivatives of rigid carboxylic acids-inhibitors of ras-dependent cell growth

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7 January 2021

Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid

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7 January 2021

How MAP kinases are regulated

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7 January 2021

Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation

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7 January 2021

Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

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7 January 2021

Chemical biology of protein isoprenylation/methylation

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7 January 2021

Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins.

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7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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7 January 2021

Mechanistic studies on human platelet isoprenylated protein methyltransferase: farnesylcysteine analogs block platelet aggregation without inhibiting the methyltransferase

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7 January 2021

Prenylated protein methyltransferase of rat cerebellum is developmentally co-expressed with its substrates

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7 January 2021

The uniquely distributed isoprenylated protein methyltransferase activity in the rat brain is highly expressed in the cerebellum

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7 January 2021

Reduction of caveolin and caveolae in oncogenically transformed cells

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7 January 2021

10.1016/S0925-4439(97)00077-X

Identifiers

DOI

1 reference

release_kymkpbzue5c3rc4gbsqhemp4jm

26 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kymkpbzue5c3rc4gbsqhemp4jm

24 November 2022

mapped directly with Wikidata item

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